20.500.12556/RUL-36562 Bactericidal effect of hydrolysable and condensed tannin extracts on Campylobacter jejuni in vitro Strategies are sought to reduce intestinal colonisation of food-producing animals by Compylobacter jejuni, a leading bacterial cause of human foodborne illness worlwide. Presently, we tested the antimicrobial activity of hydrolysable-rich blackberry, cranberry and chestnut tannin extracts and condensed tannin-rich mimosa, querbracho and sorghum tannins (each at 100 mg/mL) against C. jejuni via disc diffusion assay in the presence of supplemental casamino acids. We found that when compared to non-tannin-treated controls, all teste tannins inhibited the growth of C. jejuni and that inhibition by the condensed tannin-rich mimosa and querbracho extracts was mitigated in nutrient-limited medium supplemented with casamino acids. When tested in broth culture, both chestnut and mimosa extracts inhibited growth of C. jejuni and this inhibition was much greater in nutrient-limited than in full-strength medium. Consistent with observations from the disc diffusion assay, the inhibitory activity of the condensed tannin-rich mimosa extracts but not the hydrolysable tannin-rich chestnut extracts was mitigated by casamino acid supplementation to the nutrient-limited medium, likely because the added amino acids saturated the binding potential of the condensed tannins. These results demonstrate the antimicrobial activity of various hydrolysable and condensed tannin-rich extracts against C. jejuni and reveal that condensed tannins may be less efficient than hydrolysable tannins in controlling C. jejuni in gut environments containing high concentrations of amino acids an soluble proteins. mikrobiologija Camylobacter jejuni tanini bakteriocidi true false false Angleški jezik Angleški jezik Delo ni kategorizirano 2015-07-10 12:30:31 2015-07-10 12:30:31 2022-06-23 03:49:53 0000-00-00 00:00:00 2012 0 0 Str. 253-258 no. 4 Vol. 57 2012 0000-00-00 NiDoloceno NiDoloceno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 579 0015-5632 10.1007/s12223-012-0119-4 3046280 25470976 http://www.springerlink.com/content/k4724053553718h7/fulltext.pdf 1 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=36573 Biotehniška fakulteta 0 0 0