20.500.12556/RUL-36555 Simulated data for genomic selection and genome-wide association studies using a combination of coalescent and gene drop methods An approach is described for simulating data sequence, genotype, and phenotype data to study genomic selection and genome-wide association studies (GWAS). The simulation method, implemented in a software package called AlphaDrop, can be used to simulate genomic data and phenotypes with flexibility in terms of the historical population structure, recent pedigree structure, distribution of quantitative trait loci effect, and with sequence and single nucleotide polymorphism-phased alleles and genotypes. Ten replicates of representative scenario used to study genomic selection in livestock were generated and have been made publically available. The simulated data sets were structured to encompass a spectrum of additive quantitative trait loci effect distributions, relastionship structures, and single nucleotide polymorpism chip densities. genomika genomska selekcija genotip fenotip simulacije true false false Angleški jezik Neznan jezik Delo ni kategorizirano 2015-07-10 12:30:26 2015-07-10 12:30:26 2022-06-23 03:49:51 0000-00-00 00:00:00 2012 0 0 Str. 425-427 no. 4 Vol. 2 2012 0000-00-00 NiDoloceno NiDoloceno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 575 2160-1836 10.1534/g3.111.001297 3034248 3033992 http://www.g3journal.org/content/2/4/425.full.pdf+html 1 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=36566 Biotehniška fakulteta 0 0 0