20.500.12556/RUL-189586 PeptideVisualizer a novel software solution for PROTOMAP analysis PeptideVisualizer is an open-source software for PROTOMAP analysis, offering an intuitive graphical user interface and command-line compatibility. The software processes mass spectrometry data output from MaxQuant to visualize protein migration in polyacrylamide gel electrophoresis and sequence coverage. In addition, it integrates information regarding protein secondary structure and features from the UniProt database to visualize them within comprehensive peptographs. These features allow us to assess the occurrence of a proteolytic event based on sequence context and peptides abundance. The key advantages of PeptideVisualizer include the integration of quantitative information, handling of multiple experiments with biological replicates, and the introduction of a novel mismatch factor─a metric designed to rapidly identify proteolytic events. Herein, the software was validated in an apoptosis-related data set, demonstrating its effectiveness and usefulness in large-scale proteomic data analysis. proteolysis proteases PeptideVisualizer mass spectrometry PROTOMAP open-source software MaxQuant proteoliza proteaze PeptideVisualizer peptidi masna spektrometrija odprtokodna programska oprema true false true Angleški jezik Slovenski jezik Članek v reviji 2026-10-09 13:34:40 2026-10-09 13:34:45 2026-10-11 03:37:14 0000-00-00 00:00:00 2026 0 0 Str. 2591-2597 iss. 5 Vol. 25 May 2026 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 577 1535-3907 10.1021/acs.jproteome.5c01209 281770243 peptidevisualizer-a-novel-software-solution-for-protomap-analysis.pdf peptidevisualizer-a-novel-software-solution-for-protomap-analysis.pdf 1 DF23E5122D1CAB6015C70A982157998B cc8d46f68ce98ce29c329b8079ba396fb3f8ee3b07cc0c92209fdccbfbbba0b5 b487cfe7-c3d5-11f1-8bc5-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=250245 https://pubs.acs.org/jprobs/article/25/5/2591/5141684/PeptideVisualizer-A-Novel-Software-Solution-for 0 90a4385c-c3d5-11f1-8bc5-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=250244 Fakulteta za kemijo in kemijsko tehnologijo 0 0 0