20.500.12556/RUL-189055 Vpliv sindroma policističnih jajčnikov na dojenje diplomsko delo The impact of polycystic ovary syndrome on breastfeeding diploma work Uvod: Sindrom policističnih jajčnikov je pogosta hormonska motnja, ki prizadene ženske v rodni dobi. Za ta sindrom je značilno hormonsko neravnovesje, ki povzroča prekomerno proizvodnjo androgenih hormonov, kar lahko ovira ovulacijo in povzroči neredne ali izpuščene menstruacije. Lahko se kaže tudi z aknami, s hirsutizmom, pridobivanjem telesne mase in z odpornostjo na inzulin. Pri ženskah s sindromom policističnih jajčnikov opisujejo slabšo uspešnost dojenja. Namen: S pregledom literature raziskati in predstaviti vpliv sindroma policističnih jajčnikov na dojenje. Metode dela: Uporabili smo deskriptivno metodo dela s pregledom znanstvene in strokovne literature v slovenskem in angleškem jeziku. Literaturo smo iskali s pomočjo spletnega portala digitalne knjižnice Univerze v Ljubljani (DikUL), v bibliografskih podatkovnih zbirkah CINAHL Ultimate, PubMed, Cochrane in Medline Plus. V analizo smo vključili slovenske in angleške članke, objavljene od leta 2008 do leta 2025, ki obravnavajo povezavo med sindromom policističnih jajčnikov in dojenjem. Rezultati: Rezultati kažejo, da sindrom policističnih jajčnikov vpliva na laktacijo predvsem posredno, prek hormonskega neravnovesja in presnovnih motenj. Povišane ravni androgenih hormonov lahko zavirajo delovanje prolaktinskih receptorjev, inzulinska rezistenca pa vpliva na sintezo laktoze in s tem na volumen mleka. Pogosta je tudi zakasnjena laktogeneza II. Pomembno vlogo ima povišan indeks telesne mase, ki negativno vpliva na hormonski odziv in uspešnost dojenja. Razprava in zaključek: Ugotavljamo, da sindrom policističnih jajčnikov sam po sebi ni vedno neodvisen dejavnik za slabše izide dojenja, ampak deluje v kombinaciji z drugimi dejavniki, predvsem debelostjo. Ključna sta zgodnje prepoznavanje tveganj in ustrezna podpora materam s sindromom policističnih jajčnikov, saj lahko s celostnim pristopom izboljšamo uspešnost dojenja. Introduction: Polycystic ovary syndrome is a common hormonal disorder affecting women of reproductive age. It is characterized by hormonal imbalance, which leads to excessive production of androgen hormones, potentially interfering with ovulation and causing irregular or missed menstrual cycles. It also manifests with acne, hirsutism, weight gain and insulin resistance. Women with polycystic ovary syndrome often experience lower breastfeeding success. Purpose: To explore and present the impact of polycystic ovary syndrome on breastfeeding through a review of the literature. Methods: A descriptive research method was used, based on a review of scientific and professional literature in the Slovenian and English languages. We searched the literature using the online portal of the Digital Library of the University of Ljubljana (DikUL) and bibliographic databases such as CINAHL Ultimate, PubMed, Cochrane and Medline Plus. We included Slovenian and English articles published from 2008 to 2025 that discuss the association between polycystic ovary syndrome and breastfeeding. Results: The results indicate that polycystic ovary syndrome affects lactation primarily indirectly, through hormonal imbalance and metabolic disturbances. Elevated androgen levels may inhibit the function of prolactin receptors, while insulin resistance affects lactose synthesis and consequently milk volume. Delayed lactogenesis II is also common. A high body mass index plays an important role, negatively influencing hormonal response and breastfeeding success. Discussion and conclusion: It was found that polycystic ovary syndrome itself is not always an independent factor for poorer breastfeeding outcomes, but rather acts in combination with other factors, especially obesity. Early identification of risk factors and appropriate support for mothers with polycistic ovary syndrome are essential, as a comprehensive approach can improve breastfeeding success. diplomska dela zdravstvena nega sindrom policističnih jajčnikov dojenje androgeni hormoni inzulinska rezistenca laktogeneza laktacija diploma theses nursing care polycystic ovary syndrome breastfeeding androgens insulin resistance lactogenesis lactation true false false [T. Kuhar] Slovenski jezik Angleški jezik Diplomsko delo/naloga 2026-10-01 07:46:04 2026-10-01 07:46:06 2026-10-03 03:58:45 0000-00-00 00:00:00 2026 0 Ljubljana 0 Ljubljana VIII, 26 str. 0000-00-00 NiDoloceno NiDoloceno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 616-083 166169 293259011 65510.pdf 65510.pdf 1 C77E0EF26236026AC47E91765197B295 f535f64e8bb5d0d0e1a685673a2c8299c1baac5cc8af91e76c1a589b3384ecfc 4960a799-bd5b-11f1-8bc5-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=249498 Zdravstvena fakulteta 0 0 0