20.500.12556/RUL-187420 The effect of orthodontic tooth movement on the sensitivity of dental pulp a systematic review and meta-analysis Orthodontic tooth movement (OTM) is a process that's initiated by orthodontic forces. As a consequence, the forces could restrict pulpal blood supply, possibly affecting dental pulp. The study aimed to review the available evidence on the short and long-term effects of orthodontic tooth movement on dental pulp sensitivity and to identify clinically relevant risk factors. Sources: PubMed, Embase, Scopus, and Web of Science were searched for papers from 1990 to the end of December 2021. Study selection: The studies that evaluated dental pulp sensitivity of teeth undergoing OTM were included in the systematic review. Randomized, nonrandomized and case-controlled studies were included in the analysis. Risk of bias in each study was assessed using the ROBINS-I tool. Data: The systematic search yielded an initial sample of 1110 studies, 17 were included in qualitative analysis. Most studies were classified as moderate risk of bias, however only limited long-term evidence with a higher risk of bias exists. Electric pulp test (EPT) sensitivity threshold during active OTM was increased by 4.25 SD (P < 0.001) and the relative risk (RR) of pulpal non-sensitivity was 13.27 (P < 0.001) higher compared to pre-orthodontic baseline status. Significant differences were between subgroups associated with the type of OTM. A positive relationship between pulpal non-sensitivity and mean patient age was discovered (P = 0.041). After OTM the risk of pulpal non-sensitivity remained 5.76 times higher (P < 0.001) in the long term. Conclusions: Evidence showed that OTM could affect dental pulp sensitivity. The type of OTM and patients' age were identified as clinically relevant risk factors. Clinical significance: Orthodontic tooth movement negatively impacts the sensitivity of dental pulp during active treatment and to a lesser degree in the long term. Pulpal sensitivity tests during active OTM should therefore be interpreted with caution. Data indicates younger patients have a lower risk of negative pulpal sensitivity during orthodontic treatment. tooth movement techniques orthodontic tooth movement dental pulp dental pulp test true false true Angleški jezik Slovenski jezik Delo ni kategorizirano 2026-09-11 07:29:43 2026-09-11 07:47:19 2026-09-12 04:29:14 0000-00-00 00:00:00 2023 0 0 14 str. iss. 4, art. e14621 Vol. 9 2023 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 616.31 2405-8440 10.1016/j.heliyon.2023.e14621 149780227 RAZ_Golez_Aljaz_2023.pdf RAZ_Golez_Aljaz_2023.pdf 1 D63D8913070E6EF329471C4A97AFACE9 fd70b31af35af2ff41cbebeb14a34372633a2b76fa03f7aa1b84f8241a56b72e cb62d171-ada4-11f1-8bc5-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=247090 https://www.sciencedirect.com/science/article/pii/S2405844023018285 0 a4ee7bd5-ada4-11f1-8bc5-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=247089 Medicinska fakulteta 0 0 0