20.500.12556/RUL-187198 Assessment of potentially unnecessary antibiotic use for suspected urinary tract infections in nursing homes using a simplified algorithm Background: Nursing home (NH) residents are frequently treated with antibiotics for urinary tract infections (UTIs), often due to overdiagnosis. The aim of this study was to evaluate the proportion of potentially unnecessary antibiotic use for suspected UTIs in NHs across eight European countries. Research design and methods: Over a three-month period (February to April 2024), NH professionals recorded information on all antibiotic treatments for UTIs using a specific registration chart. Based on medical literature and the expertise of the project consortium members, the authors developed and endorsed by consensus a simplified algorithm to assess unnecessary antibiotic use in residents without indwelling catheters. Results: The study, conducted across 110 NHs, included 2773 antibiotic-treated infections. Of these, 1158 (41.8%) were treated for UTIs. Among 975 UTI cases without catheters, 54.1% may have been unnecessarily treated. Over one-third involved nonspecific symptoms including poor general condition and changes in urine appearance, while specific urinary symptoms, such as incontinence (21.3%) and dysuria (20.8%), were less common. A trend toward greater, potentially unnecessary antibiotic use was observed when urine dipsticks were performed. Conclusions: The findings reveal potentially unnecessary antibiotic use. Further algorithm validation is needed to enhance diagnostic criteria, reduce overuse, and improve UTI management in NHs. urinary tract infection anti-bacterial agents bacteriuria drug resistance frail elderly microbial nursing homes signy and symptoms urinalysis okužba sečil antibakterisjka sredstva bakteriurija odpornost na zdravila slabotni starejši mikrobni domovi za ostarele znaki in simptomi analiza urina true false true Angleški jezik Slovenski jezik Članek v reviji 2026-09-09 11:31:02 2026-09-09 11:31:05 2026-09-11 03:31:15 0000-00-00 00:00:00 2025 0 0 Str. 235-241 no. 2/4 Vol. 23 2025 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 616.6 1478-7210 10.1080/14787210.2025.2456860 226219523 RAZ_Llor_Carl_2025.pdf RAZ_Llor_Carl_2025.pdf 1 6535814D52EE31A9D592F527DFE2D31A 88df07bd0bd2b3682390f5de5d201dcbae901dffa9c183aa16bb0f0ae558699b 7601e7bf-ac31-11f1-8bc5-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=246692 https://www.tandfonline.com/doi/full/10.1080/14787210.2025.2456860?rfr_dat=cr_pub++0pubmed&url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org 1 28f2f23b-ac31-11f1-8bc5-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=246688 Medicinska fakulteta 0 0 0