20.500.12556/RUL-187174 Genitourinarni sindrom v menopavzi pri onkoloških bolnicah diplomsko delo Genitourinary syndrome of menopause in oncology patients diploma work Uvod: Genitourinarni sindrom v menopavzi je pogost in pogosto tudi spregledan sindrom, ki pomembno vpliva na kakovost življenja žensk. Pri onkoloških bolnicah, zlasti po raku dojke in ginekoloških rakih, se zaradi kemoterapije, obsevanja in kirurške odstranitve jajčnikov simptomi razvijejo prej kot pri fiziološki menopavzi in so izrazitejši ter dolgotrajnejši. Namen: Namen diplomskega dela je s pregledom literature predstaviti genitourinarni sindrom v menopavzi pri ženskah po onkološkem zdravljenju, s poudarkom na najpogosteje opisanih simptomih, vplivu na kakovost življenja, možnostih obravnave pri ženskah s hormonsko odvisnim rakom ter vlogo zdravstvenih delavcev pri obravnavi genitourinarnega sindroma v menopavzi. Metode dela: Izveden je bil pregled strokovne in znanstvene literature v podatkovnih bazah PubMed, Medline in ScienceDirect, objavljene med leti 2015–2026, v slovenskem in angleškem jeziku. Postopek izbora je bil prikazan z diagramom PRISMA. Rezultati: V končni pregled literature je bilo vključenih 14 zadetkov. Genitourinarni sindrom v menopavzi je pri onkoloških bolnicah zelo pogost. Najpogosteje se pojavljajo simptomi, kot so suha nožnica, disparevnija, motnje spolne funkcije ter urološke težave. Onkološko zdravljenje pomembno prispeva k razvoju in poslabšanju simptomov. Pri hormonsko odvisnih rakih igrajo pomembno vlogo nehormonski ukrepi (lubrikanti, vlažilci, hialuronska kislina, lidokain), izključena pa ni niti lokalna estrogenska terapija, ki se uporablja po individualni presoji z onkologom. Zdravstveni delavci imajo ključno vlogo pri zgodnjem prepoznavanju simptomov, aktivnem izpraševanju o težavah in simptomih ter svetovanje in usmerjanje v ustrezno zdravljenje. Razprava in zaključek: Genitourinarni sindrom v menopavzi pri onkoloških bolnicah pogosto ostaja nenaslovljen zaradi sramu bolnic ali pomanjkanja aktivnega izpraševanja zdravstvenih delavcev. Individualizirana obravnava z uravnoteženim vključevanjem hormonskih in nehormonskih pristopov ter zgodnje prepoznavanje simptomov lahko bistveno izboljšata kakovost življenja teh bolnic. Introduction: Genitourinary syndrome of menopause is a common and often overlooked condition that significantly affects woman's quality of life. In oncology patients, especially those after breast cancer and gynecologic malignancies, symptoms develop earlier than in physiological menopause and tend to be more severe and long-lasting due to chemotherapy, radiotherapy and surgical oophorectomy. Purpose: Purpose of this thesis is, through a literature review, to present genitourinary syndrome in menopause in woman after oncological treatment, with a focus on the most commonly reported symptoms, its impact on quality of life, treatment options for woman with hormone-dependent cancer, and the role of healthcare workers in the management of genitourinary syndrome of menopause. Methods: A review of professional and scientific literature was conducted in the PubMed, Medline and ScienceDirect databases for articles published between 2015 and 2026 in Slovenian and English language. The selection process was presented using a PRISMA flow diagram. Results: A total of 14 studies were included in the literature review. Genitourinary syndrome of menopause is very common in oncology patients. The most fequently reported symptoms are vaginal dryness, dyspareunia, sexual dysfunction and urological problems. Cancer treatment significantly contributes to the development and worsening of these symptoms. In hormone-dependent cancers, non-hormonal measures (lubricants, moisturizers, hyaluronic acid, lidocain) play key role; local estrogen therapy is not absolutely excluded but may be used on an individual basis in consultation with the oncologist. Healthcare workers have a key role in the early recognition of symptoms, actively inquiring about problems and complaints, and in providing counseling and guidance toward appropriate treatment. Discussion and conclusion: Genitourinary syndrome of menopause in oncology patients often remains unaddressed due to patients's feelings of shame or lack of proactive questioning by healthcare professionals. Individualized management with a balanced use of hormonal and non-hormonal approaches, together with early recognition of symptoms, can substantially improve the quality of life of these patients. diplomska dela babištvo genitourinarni sindrom v menopavzi onkološke bolnice menopavza zdravljenje genitourinarnega sindroma hormonsko odvisni rak vloga zdravstvenih delavcev diploma theses midwifery genitourinary syndrome in menopause oncology patients menopause treatment of genitourinary syndrome hormone-dependent cancer the role of healthcare professionals true false false [T. Porle] Slovenski jezik Angleški jezik Diplomsko delo/naloga 2026-09-09 10:06:36 2026-09-09 10:06:38 2026-09-10 04:31:16 0000-00-00 00:00:00 2026 0 Ljubljana 0 Ljubljana IX, 35 str. 0000-00-00 NiDoloceno NiDoloceno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 618.2/.7 163742 290491651 64090.pdf 64090.pdf 1 B5A354155352CFC39D4DF19602502092 c17122ada2a0af52f30351aa0418ad93448cc710734311bd6ce77756bb0280ce 5c3b4dea-ac25-11f1-8bc5-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=246634 Zdravstvena fakulteta 0 0 0