20.500.12556/RUL-186950 Vpliv strukture aromatskih spojin na potek aciliranja The influence of the structure of aromatic compounds on the course of acylation V svojem diplomskem delu sem primerjal potek aciliranja aromatskih spojin na klasičen način po Friedel–Craftsu, z uporabo acetil klorida in aluminijevega triklorida v suhem diklorometanu, ter »zelen« način, kjer reakcija poteče v trifluoroocetni kislini ob prisotnosti acetanhidrida. V tej reakciji nastopa trifluoroocetna kislina kot reakcijski medij in katalizator. Prednost slednje je možnost ponovne uporabe in manjša količina kemijskega odpadka, ki pri reakciji nastane v primerjavi s klasičnim aciliranjem. V primerih, kjer zeleno aciliranje poteče, je po izkoristkih in zahtevnosti nadaljnjega čiščenja primerljivo s klasičnim. Pripravljene produkte sem po sintezi očistil in analiziral z 1H NMR in IR spektroskopijo ter masno spektrometrijo. In my thesis, I compared the course of acylation of aromatic compounds between a classic Friedel–Crafts method, using acetyl chloride and aluminium trichloride in dry dichloromethane and “green” method, where the reaction is conducted in trifluoroacetic acid and with acetic anhydride. In the latter reaction, the trifluoroacetic acid is acting both as a reaction medium and catalyst. The core benefit of the green acylation is the reusability of TFA and smaller chemical waste production compared to classic acylation. In cases where reactions with green acylation were successful, the yields and complexity of further purification were comparable to classic acylation. I purified all synthesised products and analysed them with 1H NMR, IR spectroscopy and mass spectrometry. aciliranje aromatske spojine trifluoroocetna kislina trajnostni način klasični način acylation aromatic compounds trifluoroacetic acid classical approach sustainable approach true false false Slovenski jezik Angleški jezik Diplomsko delo/naloga 2026-09-07 14:20:03 2026-09-07 14:20:08 2026-09-08 04:19:44 0000-00-00 00:00:00 2026 0 0 0000-00-00 NiDoloceno NiDoloceno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 1970-01-01 25696 Sadl_Jernej_-_Vpliv_strukture_aromatskih_spojin_na_potek_aciliranja.pdf Sadl_Jernej_-_Vpliv_strukture_aromatskih_spojin_na_potek_aciliranja.pdf 1 9436E615F49CF523BEEB503986936DED e4eaf9bd5906007167e0e55b29ca35619a733287778ee55124e67acf60abb2a8 73e1aebf-aab6-11f1-8bc5-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=246353 Fakulteta za kemijo in kemijsko tehnologijo 0 0 0