20.500.12556/RUL-186943 Incorporation of the trifluoromethylthio group ($CF_3S−$) into biomolecules a versatile tool for advancing life sciences The trifluoromethylthio functional group (CF$_3$S-) has gained considerable attention in synthetic and medicinal chemistry due to its ability to enhance the pharmacokinetic profiles of functionalized compounds. This Synopsis highlights recent progress in the incorporation of the CF$_3$S group into biomolecules and bioactive compounds, with a focus on its influence on physicochemical properties and its applications in medicinal chemistry and chemical biology. fluorine biomolecules peptides amino acids NMR spectroscopy pharmacokinetics fluor biomolekule peptidi aminokisline NMR spektroskopija farmakokinetika true false true Angleški jezik Slovenski jezik Članek v reviji 2026-09-07 13:14:30 2026-09-07 13:14:30 2026-09-08 04:19:42 0000-00-00 00:00:00 2026 0 0 Str. 8473-8486 iss. 25 Vol. 91 26 Jun. 2026 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 546.16:547.9 0022-3263 10.1021/acs.joc.6c00904 282047235 RAZ_Gregorc_Jure_2026.pdf RAZ_Gregorc_Jure_2026.pdf 1 6908D940866BEB35E984019270EB61A2 eaae62f368a8f946d499d4dede6ceed29f4fc4503fd4eb040cf32da9d76bd37a d62015cd-aaad-11f1-8bc5-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=246344 https://pubs.acs.org/doi/10.1021/acs.joc.6c00904 1 498a9fa9-aaad-11f1-8bc5-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=246343 Fakulteta za kemijo in kemijsko tehnologijo 0 0 0