20.500.12556/RUL-186851 Statin adherence in atherosclerotic disease research data underlying the article Aims: To evaluate post-discharge statin adherence and its association with clinical outcomes after hospitalisation for atherosclerotic cardiovascular disease (ASCVD). Methods: In this nationwide Slovenian cohort, hospital, pharmacy, and vital-status data were linked for adults hospitalised with coronary artery, cerebrovascular, or peripheral artery disease between 2015 and 2022. Statin adherence was assessed as time-varying rolling 365-day proportion of days covered (PDC) and 120-day CMA7. The outcome was all-cause death or rehospitalisation for ASCVD. Results: Of 82,083 patients in the 30-day landmark cohort, 62,932 had at least one post-discharge statin dispensing. Overall, 23% had no recorded post-discharge dispensing, rising to 30% in peripheral artery disease. Higher adherence was independently associated with lower risk of the composite outcome: each 10-percentage-point increase in PDC and CMA7 was associated with a hazard ratio of 0.96 (95% CI 0.96–0.97; both p<0.001). Conclusion: Better longitudinal statin adherence was associated with lower risk of death or recurrent ASCVD hospitalisation, while substantial treatment gaps remained, particularly in peripheral artery disease. atherosclerotic cardiovascular disease statins medication adherence persistence secondary prevention aterosklerotična srčno-žilna bolezen statini adherenca k zdravljenju z zdravili vztrajnost pri zdravljenju sekundarna preventiva true false false Angleški jezik Slovenski jezik Slovenia 2015-2022 Neznano 2026-09-05 13:10:08 2026-09-10 14:57:19 2026-09-11 04:28:07 0000-00-00 00:00:00 2026 0 0 0000-00-00 NiDoloceno NiDoloceno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 Source_Data_Statin_Adherence_ASCVD.pdf Source_Data_Statin_Adherence_ASCVD.pdf Source Data Statin Adherence ASCVD 1 4A4B8E060C803889163C32B6E601C82F 59d8b1cd7793d34485211c79d04ca08e593bdcf25ab0eabf5bde06c64c80a478 849a5e4b-a91a-11f1-8bc5-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=246228 Medicinska fakulteta Sinteza Združevanje Drugi 0 0 0