20.500.12556/RUL-186393 Razvoj modela filmskega oblaganja tablet z uporabo metode Monte Carlo Development of a tablet film coating model using the Monte Carlo method Filmsko oblaganje tablet je kompleksen proces, pri katerem vhodni parametri razprševanja, nastavitve oblagalnega kotla in pogoji sušenja vplivajo na kakovost izdelkov ter učinkovitost procesa. Na osnovi pregleda literature smo kot glavne mehanizme procesa opredelili atomizacijo, variabilnost nanosa in sušenje. Na podlagi teh, smo v programskem jeziku Python, uporabili Monte Carlo metodo za razvoj modelov. Ugotovili smo, da optimizacija velikosti kapljic in režima sušenja ter zmanjšanje variabilnosti oblaganja ključno prispevajo k izboljšanju učinkovitosti procesa. Razviti model omogoča uporabne analize za povečanje proizvodnega obsega. Tablet film coating is a complex process in which spray input parameters, coating pan settings, and drying conditions influence product quality and process efficiency. Based on a literature review, atomization, coating variability and drying were identified as the main mechanisms in the process. Based on these, with implementation through the Python programming language, the Monte Carlo method was used for the development of models. We found that the optimization of droplet size and drying regime, together with the reduction of coating variability, make a key contribution to improving process efficiency. The developed model enables useful analyses for increasing production scale. filmsko oblaganje tablete Monte Carlo metoda atomizacija variabilnost oblaganja sušenje tablet film coating Monte Carlo method atomization coating variability drying true false false [D. Vinkovič] Slovenski jezik Angleški jezik Diplomsko delo/naloga 2026-09-01 08:31:03 2026-09-01 08:31:11 2026-09-03 04:37:43 0000-00-00 00:00:00 2026 0 Ljubljana 0 XIII, 51, [4] f. 0000-00-00 NiDoloceno NiDoloceno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 004.896:615.453.6(043.2) 288716 289548035 48738.pdf 48738.pdf 1 E868CD43E67EEB7E86BF9D3CE3E36632 ba1e623a36b8c0c3ef05d14edf58c3335bae960de22fe7bf0d25453a01e9fccd 4c3feabd-a5ce-11f1-9b0d-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=245633 Fakulteta za strojništvo 0 0 0