20.500.12556/RUL-185914 Uporaba probiotikov v terapevtske namene Use of probiotics for therapeutic purposes Diplomsko delo obravnava uporabo probiotikov v terapevtske namene. Predstavljene so značilnosti najpogosteje uporabljenih probiotičnih sevov ter njihovi mehanizmi delovanja. Na podlagi pregleda znanstvene literature so obravnavana glavna področja terapevtske uporabe probiotikov, vključno z boleznimi prebavil, presnovnimi motnjami in drugimi zdravstvenimi stanji. Pozornost je bila namenjena tudi raziskavam, ki se osredotočajo na njihovo delovanje pri zdravljenju psiholoških motenj in alergij. Poleg tega je opisano, na katera zdravstvena stanja in na katere značilnosti sevov se znanstveniki osredotočajo pri pridobivanju novih probiotičnih sevov s pomočjo genskega inženiringa. Poseben poudarek je namenjen tudi pomislekom, povezanim z njihovo uporabo, kot so razlike v kliničnih dokazih, pomanjkanje razumevanja njihovega učinkovanja ter vprašanja varnosti pri določenih skupinah bolnikov. Pregled literature kaže, da imajo nekateri probiotični sevi potencialne koristi pri podpori zdravljenja posameznih bolezni, vendar se učinkovitost med različnimi sevi in pacienti razlikuje. Za zanesljivo vrednotenje njihove terapevtske uporabe ter boljše razumevanje njihovega delovanja pa so potrebne nadaljnje klinične raziskave. This bachelor's thesis examines the use of probiotics for therapeutic purposes. It presents the characteristics of the most commonly used probiotic strains and their mechanisms of action. Based on a review of the scientific literature, the main areas of the therapeutic application of probiotics are discussed, including gastrointestinal diseases, metabolic disorders, and other health conditions. Attention was also given to researches which focus on efficiency of healing psychological disorders and allergies with probiotics. In addition, It is described on which health conditions and strain characteristics researchers focus mostly, when developing new probiotic strains through genetic engineering. Focus was also given to concerns associated with their use, such as variations in clinical evidence, the limited understanding of their mechanisms of action, and safety issues in certain patient populations. The literature review indicates that some probiotic strains may provide benefits in supporting the treatment of specific diseases; however, their effectiveness varies among different strains and patients. Further clinical research is needed to reliably evaluate their therapeutic use and to gain a better understanding of their mechanisms of action. probiotik bolezensko stanje terapevtik učinkovitost raziskave probiotic disease therapeutic efficiency researches true false false Slovenski jezik Angleški jezik Diplomsko delo/naloga 2026-08-23 07:16:39 2026-08-23 07:16:48 2026-08-25 14:31:07 0000-00-00 00:00:00 2026 0 0 0000-00-00 NiDoloceno NiDoloceno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 285495 288839427 60405.pdf 60405.pdf 1 5536A9A66E6B2075D34A7A856EDDC2A9 4b430d385e624bddc2f9587e4e673df7ea5ddc2f5dda0a2b064063ccfbbfe266 719435d8-9eb1-11f1-9b0d-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=244921 Biotehniška fakulteta 0 0 0