20.500.12556/RUL-185093 Vpliv oralnih hormonskih kontraceptivov na stopnjo presnove v mirovanju (RMR) The effect of oral hormonal contraceptives on resting metabolic rate (RMR) Oralna hormonska kontracepcija (OHK) je med ženskami razširjena oblika podpiranja ali uravnavanja rednega menstrualnega cikla, zagotavljanja zaščite pred nosečnostjo in urejanja hormonskih neravnovesij. Med menstrualnim ciklom je stopnja presnove v mirovanju (angl. Resting metabolic rate – RMR) precej variabilna. Uživanje OHK bi lahko prek vnosa eksogenih sintetičnih spolnih hormonov, ki zmotijo naraven ovarijski hormonski profil, lahko imelo posledice na RMR. Opravili smo narativni pregled literature z namenom proučiti učinke endogenih in eksogenih spolnih hormonov na RMR ter morebitne razlike v vplivu pri uporabi progestinske OHK in kombinirane OHK. Rezultati redkih raziskav, ki proučujejo učinek OHK na RMR, so neenotni. Prepletenosti številnih fizioloških mehanizmov, ki vključujejo termoregulacijo, uravnavanje apetita, hormonsko ravnovesje ter spremembe v telesni sestavi, nakazujejo možnost vpliva OHK na presnovno aktivnost žensk. Kljub temu pa trenutno razpoložljivi dokazi ne omogočajo oblikovanja trdnih in enoznačnih zaključkov. Morebitni vpliv OHK na RMR ostaja nejasen, kar poudarja potrebo po nadaljnjih raziskavah za poglobljeno razumevanje ženske fiziologije. Glede na pogosto uporabo OHK tudi med športnicami in njihovega morebitnega vpliva na presnovo je nujno, da se njihov vpliv temeljiteje prouči in hkrati okrepi tudi vključevanje žensk v raziskave o presnovi. Oral hormonal contraception (OHC) is a widely used method among women for supporting or regulating menstrual cycles, providing protection against pregnancy, and managing hormonal imbalances. During the menstrual cycle, there is considerable variability in resting metabolic rate (RMR). The intake of OHC, through the introduction of exogenous synthetic sex hormones that disrupt the natural ovarian hormonal profile, could potentially affect RMR. We conducted a narrative literature review to examine the effects of endogenous and exogenous sex hormones on RMR, as well as potential differences in the impact of progestin-only versus combined OHC. The findings from the limited number of studies investigating the effect of OHC on RMR are inconsistent. The interplay of numerous physiological mechanisms, including thermoregulation, appetite regulation, hormonal balance, and changes in body composition, suggests that OHC may influence women's metabolic activity. However, the currently available evidence does not allow for conclusive statements. The potential impact of OHC on RMR remains unclear, highlighting the need for further research to deepen our understanding of female physiology. Given the widespread use of OHC among female athletes and its possible influence on metabolism, it is essential to examine its effects more thoroughly and to strengthen the inclusion of women in metabolic research. šport telesna aktivnost oralna hormonska kontracepcija stopnja presnove v mirovanju poraba energije v mirovanju presnova spolni hormoni sport physical activity oral hormonal contraception resting metabolic rate resting energy expenditure metabolism sex hormones true false true Slovenski jezik Angleški jezik Članek v reviji 2026-07-22 12:50:27 2026-07-22 12:50:29 2026-07-23 04:10:11 0000-00-00 00:00:00 2025 0 0 Str. 61-67 št. 3/4 Letn. 73 2025 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 796.01 3024-0603 10.52165/sport.73.3-4.61-67 265072643 SPORT+3-4-25_061-067_Novak.pdf SPORT+3-4-25_061-067_Novak.pdf 1 8259ADCDE1AE27B8C0E4016346AAFC64 138ddf2d11ab9fe41ed194788bb5f6b3f9e3c7dbba03a9bf742e74eb32d599f7 09768f20-85bc-11f1-9b0d-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=243279 https://journals.uni-lj.si/sport/article/view/23205 1 e9564f7f-85ba-11f1-9b0d-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=243278 Fakulteta za šport Šport 0 0 0