20.500.12556/RUL-184573 Diagnostika in zdravljenje raka materničnega vratu v nosečnosti diplomsko delo Diagnosis and treatment of cervical cancer in pregnancy diploma work Uvod: Rak materničnega vratu v nosečnosti je redko, vendar klinično zahtevno stanje, saj je pri diagnostiki in zdravljenju treba upoštevati zdravje matere ter varnost ploda. Obravnava zahteva individualiziran in multidisciplinaren pristop. Namen: Namen diplomskega dela je bil s pregledom strokovne literature proučiti obravnavo raka materničnega vratu v nosečnosti, opredeliti najprimernejše diagnostične in terapevtske postopke ter raziskati vpliv zdravljenja na nosečnost in plod. Metode dela: Uporabili smo deskriptivno metodo dela s sistematičnim pregledom strokovne in znanstvene literature. Iskanje literature je potekalo v podatkovnih bazah PubMed, CINAHL in DiKul. V končno analizo je bilo vključenih 13 člankov, objavljenih med letoma 2016 in 2026. Rezultati: Ugotovili smo, da nosečnost sama po sebi ne poslabša prognoze bolnic z rakom materničnega vratu, kadar je bolezen pravočasno diagnosticirana in ustrezno zdravljena. Varne diagnostične metode v nosečnosti so PAP bris, kolposkopija z biopsijo in MRI medenice. Zdravljenje je odvisno od stadija bolezni, gestacijske starosti ploda, histološkega tipa tumorja ter želje bolnice glede nadaljevanja nosečnosti. Pri zgodnjih stadijih se lahko uporabi kirurško zdravljenje, pri napredovalih stadijih pa po prvem trimesečju neoadjuvantna kemoterapija. Razprava in zaključek: Najpogostejši zaplet zdravljenja raka materničnega vratu v nosečnosti je prezgodnji porod, medtem ko so večje prirojene nepravilnosti pri plodu redke. Ob pravočasni diagnostiki, ustreznem zdravljenju in multidisciplinarni obravnavi je v številnih primerih mogoče doseči ugodne izide za mater in plod. Pomembno vlogo ima tudi babica, ki sodeluje pri zdravstveni vzgoji, podpori nosečnici in zagotavljanju kontinuirane obravnave. Introduction: Cervical cancer during pregnancy is a rare but clinically challenging condition, as both maternal health and fetal safety must be considered during diagnosis and treatment. Management therefore requires an individualized and multidisciplinary approach. Purpose: The purpose of the thesis was to review the professional literature to study the treatment of cervical cancer during pregnancy, to define the most appropriate diagnostic and therapeutic procedures, and to investigate the impact of treatment on pregnancy and the fetus. Methods: A descriptive method with a systematic review of professional and scientific literature was used. Literature was searched in the PubMed, CINAHL, and DiKul databases. A total of 13 articles published between 2016 and 2026 were included in the final analysis. Results: The review showed that pregnancy itself does not worsen the prognosis of patients with cervical cancer when the disease is diagnosed early and treated appropriately. Safe diagnostic methods during pregnancy include the PAP smear, colposcopy with biopsy, and pelvic MRI. Treatment depends on the stage of the disease, gestational age of the fetus, histological type of the tumor, and the patient’s wish regarding continuation of the pregnancy. In early stages, surgical treatment may be performed, while in more advanced stages neoadjuvant chemotherapy may be used after the first trimester. Discussion and conclusion: The most common complication of cervical cancer treatment during pregnancy is preterm birth, whereas major congenital abnormalities in the fetus are rare. With timely diagnosis, appropriate treatment, and multidisciplinary management, favorable outcomes for both the mother and the fetus can often be achieved. An important role is also played by the midwife, who participates in health education, provides support to the pregnant woman, and ensures continuous care. diplomska dela babištvo rak materničnega vratu nosečnost diagnostika zdravljenje multidisciplinarna obravnava diploma theses midwifery cervical cancer pregnancy diagnosis treatment multidisciplinary management true false false [Š. Makari] Slovenski jezik Angleški jezik Diplomsko delo/naloga 2026-07-10 07:46:40 2026-07-10 07:46:42 2026-07-15 08:51:34 0000-00-00 00:00:00 2026 0 Ljubljana 0 Ljubljana IX, 34 str. 0000-00-00 NiDoloceno NiDoloceno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 618.2/.7 160420 284830979 59457.pdf 59457.pdf 1 F6266AE47992EF8153E43344DAD38B2A fe997764c4a4a0b6aea307d3e0c12ee97aba89464f80a3e023b0c0fb7eab8dc2 98c8390d-7c22-11f1-9b0d-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=237464 Zdravstvena fakulteta 0 0 0