20.500.12556/RUL-184340 Ekološki in prehranski vidik bazidiomicet z zapisom za egerolizine Ecological and edibility aspect of basidiomycetes coding for aegerolysins Egerolizini so biotehnološko zanimiva skupina proteinov. Zanje je značilno, da imajo relativno nizko molekulsko maso 15–17 kDa, so β-strukturirani in se specifično vežejo na nekatere membranske lipide. Nanje se lahko nato veže druga skupina partnerskih proteinov MACPF. Mešanica egerolizinov in MACPF je lahko toksična za določene vrste celic. Obstaja 155 vrst bazidiomicet, za katere smo ugotovili, da imajo v genomu zapis za egerolizine, njihove partnerske proteine MACPF ali oboje. Tem vrstam smo s pomočjo bioinformatskih analiz določili ekološko nišo in prehranski vidik. Večina teh gliv zaseda tri ekološke niše: so saprotrofi, simbionti ali paraziti. Te glive in njihova plodišča smo opredelili tudi glede na njihovo užitnost za človeka: so užitne, neužitne, pogojno užitne ali strupene. Aegerolysins are a biotechnologically relevant family of proteins. They have a relatively low molecular mass of 15–17 kDa, a predominantly β-sheet secondary structure, and high specificity for binding selected membrane lipids. These proteins can serve as docking platforms for a second protein group, MACPF proteins. The combination of aegerolysins and MACPF proteins can exhibit cytotoxic activity toward specific cell types. A total of 155 basidiomycete species have been identified whose genomes encode aegerolysins, their MACPF partner proteins, or both. Using bioinformatic analyses, we inferred the ecological niches and nutritional strategies of these species. In macrofungi, three principal ecological lifestyles have been distinguished: saprotrophic, symbiotic, and parasitic. Fungal species and their fruiting bodies have been classified according to their edibility for humans, falling into the categories of edible, inedible, conditionally edible, or toxic. Bazidiomiceta saprotrof simbiont parazit bela trohnoba rjava trohnoba ektomikorizna užitna neužitna strupena basidiomycota saprotroph symbiont parasite white rot brown rot ectomycorrhizal edible inedible toxic true false false Slovenski jezik Angleški jezik Diplomsko delo/naloga 2026-07-05 07:16:20 2026-07-05 07:16:25 2026-07-06 11:11:33 0000-00-00 00:00:00 2026 0 0 0000-00-00 NiDoloceno NiDoloceno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 280500 283720195 58056.pdf 58056.pdf 1 DF3C1ADF97D2AD89157DAF7DB1491092 260a29230c97aca3b050e0241d7f7b64eb7fec22dc57d6f171cf2c5d333190c9 8e138cc8-7830-11f1-9b0d-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=237020 Biotehniška fakulteta 0 0 0