20.500.12556/RUL-184295 Magnetic stimulation in the treatment of urgency urinary incontinence a randomized sham‑controlled clinical trial Introduction and Hypothesis Magnetic stimulation is a noninvasive, painless neuromodulatory therapy that has emerged as a promising conservative treatment for urinary incontinence. This study aimed to evaluate its clinical effectiveness and safety in women with urgency urinary incontinence (UUI). Methods In this single-centre, prospective randomised controlled trial, 70 women with UUI were randomised in a 2:1 ratio to active MS or sham treatment. Participants received 12 sessions of magnetic stimulation over 6 weeks. The active group received individually adjusted stimulation intensity, while the sham group received minimal stimulation to preserve blinding. The primary outcome was change in symptom severity measured by the International Consultation on Incontinence Questionnaire–Urinary Incontinence Short Form (ICIQ-UI SF). Secondary outcomes included bladder diary parameters (urinary frequency, urgency urinary incontinence episodes, nocturia), symptom-specific quality of life (UDI-6, IIQ-7), and patient-reported improvement (PGI-I). Outcomes were assessed at baseline and 6 months post-treatment. Results At 6 months, 40 participants in the active group and 16 in the sham group completed follow-up. The active group demonstrated significantly greater improvement in ICIQ-UI SF scores (mean change −4.05 ± 3.23) compared to sham (−1.19 ± 1.72; p < 0.001). Significant improvements were also observed in urgency incontinence episodes, nocturia, and quality of life measures in the active group. No serious adverse events were reported, confirming the favourable safety profile of MS. Conclusions This study provides new controlled evidence supporting MS as an effective, noninvasive, and well-tolerated treatment for women with UUI. These findings contribute important data on mid-term efficacy but highlight the need for further high-quality RCTs with standardised protocols and longer-term follow-up. magnetic stimulation urinary incontinence urgency urinary incontinence conservative treatment magnetna stimulacija urinska inkontinenca urgentna urinska inkontinenca konzervativno zdravljenje true false true Angleški jezik Slovenski jezik Članek v reviji 2026-07-03 08:53:43 2026-07-03 08:53:51 2026-07-04 04:21:58 0000-00-00 00:00:00 2026 0 0 Str. 1593-1603 iss. 6 Vol. 37 2026 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 618.1 1433-3023 10.1007/s00192-025-06491-6 263412227 s00192-025-06491-6.pdf s00192-025-06491-6.pdf 1 E589F730ACA35F2833FDA5F802998B71 3a62f12deed459eaabc5b841d045c90126d842ca61e0b09bbffdb98b9c23952c 3b7d9231-76ac-11f1-9b0d-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=236935 https://link.springer.com/article/10.1007/s00192-025-06491-6 1 d928d128-76ab-11f1-9b0d-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=236934 Medicinska fakulteta Pedagoška fakulteta 0 0 0