20.500.12556/RUL-184168 Umetna prekinitev nosečnosti z zdravili do 10. tedna nosečnosti varnost izvedbe metode v domačem okolju v primerjavi z bolnišničnim okoljem Medical abortion up to 10 weeks of gestation comparison of the safety of the procedure in a home setting to a hospital setting Izhodišča: Številne raziskave so dokazale varnost, sprejemljivost in zadovoljstvo z umetno prekinitvijo nosečnosti (UPN) z zdravili doma, kar odslikavajo smernice zdravstvenih združenj, med njimi tudi Svetovne zdravstvene organizacije. Kljub temu nekatere slovenske bolnišnice te možnosti še vedno ne omogočajo. Namen naše raziskave je oceniti učinkovitost, varnost in sprejemljivost UPN z zdravili v domačem okolju v primerjavi z bolnišničnim okoljem. Metode: V raziskavo so bile med 20. decembrom 2023 in 31. julijem 2024 povabljene tiste pacientke, ki so želele UPN z zdravili in so bile zaradi tega v obravnavi na Kliničnem oddelku za reprodukcijo Ginekološke klinike Univerzitetnega kliničnega centra Ljubljana. Podatke smo pridobili z anonimnim spletnim vprašalnikom, ki so ga preiskovanke dobile na svoj e-poštni naslov 2 meseca po UPN. Rezultati: V času raziskave je UPN opravilo 407 pacientk. Na spletni vprašalnik je v celoti odgovorilo 65 preiskovank, ki so UPN opravile doma, in 7, ki so UPN opravile v bolnišnici. Učinkovitost UPN z zdravili je bila večja pri tistih, ki so UPN opravile v domačem okolju. Varnost in stopnja zapletov je bila primerljiva. Preiskovanke, ki so UPN opravile v domačem okolju, so poročale v povprečju o hujših bolečinah. Večina preiskovank v obeh skupinah je bila zadovoljnih s seznanjanjem in s samim postopkom. UPN z zdravili se je zdel obema skupinama sprejemljiv. Zaključek: Raziskava je potrdila rezultate raziskav iz tujine. Kaže, da je UPN z zdravili doma tudi v slovenskem okolju varna, učinkovita in sprejemljiva, ter da so pacientke s takim postopkom zadovoljne. Background: Numerous studies have demonstrated safety, acceptability, and satisfaction with medical abortion (MA) performed at home, as reflected in the guidelines of various healthcare organizations, including the World Health Organization. Despite this, some Slovenian hospitals still do not offer this option. Our study aims to evaluate the effectiveness, safety, and acceptability of home-based MA compared to hospital-based MA. Methods: Between December 20, 2023, and July 31, 2024, patients seeking medical abortion and treated at the Department of Human Reproduction, Division of Obstetrics and Gynaecology, University Medical Centre Ljubljana, were invited to participate in the study. Data were collected through an anonymous online questionnaire sent to the participants’ email addresses two months after their MA. Results: During the study period, 407 patients underwent MA. Sixty-five patients with a home-based MA and seven patients with a hospital-based MA completed the questionnaire in full. The effectiveness of home-based MA was higher than that of hospital-based MA. Safety and complication rates were comparable. Patients who had home-based MA reported, on average, more severe pain. The majority of participants in both groups were satisfied with the counseling and the procedure itself. Medical abortion was deemed acceptable by both groups. Conclusion: Our findings confirmed the results of foreign research. They show that home-based medical abortion is safe, effective, acceptable, and satisfactory for patients in the Slovenian setting. telemedicina mifepriston mizoprostol učinkovitost sprejemljivost prekinitev nosečnosti telemedicine mifepristone misoprostol effectiveness acceptability medical abortion true false true Slovenski jezik Angleški jezik Članek v reviji 2026-07-01 10:18:55 2026-07-01 10:18:55 2026-10-08 09:43:23 0000-00-00 00:00:00 2025 0 0 Str. 289–296 št. 11/12 Letn. 94 nov./dec. 2025 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 618.39 1318-0347 10.6016/ZdravVestn.3619 265591043 RAZ_Bencina_Ursa_2025.pdf RAZ_Bencina_Ursa_2025.pdf 1 4E6ED89FB27423C2C25E4E65FB8EBF65 1872f7d93d24017907b66b7d282a90a535d6111052e5351450c3f40704b0ebee 964e3f60-7525-11f1-9b0d-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=236715 https://vestnik.szd.si/index.php/ZdravVest/article/view/3619 1 66900106-7525-11f1-9b0d-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=236714 Medicinska fakulteta 0 0 0