20.500.12556/RUL-183682 Prehabilitation with low-load blood flow restricted resistance exercise training attenuates muscle inhibition of quadriceps femoris muscle in polytraumatized patient a case report Background: Severe knee trauma and chronic cruciate ligament insufficiency are commonly accompanied by marked quadriceps femoris (QF) atrophy and weakness. High-load strengthening is often poorly tolerated by patients with compromised joint stability; therefore, low-load blood flow restriction resistance training (LL-BFRT) may serve as an effective alternative. Case presentation: A 38-year-old male presented 27 months after motorcycle-related polytrauma with right knee pain, instability, complete anterior and posterior cruciate ligament ruptures, and partial QF denervation after femoral nerve injury. Before surgery, he completed a supervised 5-week LL-BFRT prehabilitation program (13 sessions). Results: Lean thigh circumference increased by 5.9% proximally and 17.7% distally. Voluntary activation increased from 87.2% to 92.5%, and maximal QF EMG median frequency decreased by 7.4%. Knee extensor isometric and concentric (60°/s) peak torque increased by 52.4% and 36.9%, respectively. QF isometric endurance time increased from 48.5 to 61.8 s. Stair-climbing time decreased from 18.9 to 10.6 s, repetitions in the step-down test increased from 10 to 17, and the Y-balance test composite score increased from 77.7% to 99.4%. Conclusions: Substantial physiological and clinical improvements in QF voluntary activation, maximal strength, endurance, and lower limb function were observed following a short-term LL-BFRT program in a patient with multiple ligament injuries. Changes in lean thigh circumference were consistent with possible improvements in muscle size; however, muscle hypertrophy was not directly assessed. ischaemic training voluntary muscle activation polytrauma knee musculoskeletal injuries ishemični trening hotna mišična aktivacija politravma koleno mišično-skeletne poškodbe true false true Angleški jezik Slovenski jezik Članek v reviji 2026-06-17 09:36:51 2026-06-17 09:36:53 2026-08-21 08:14:30 0000-00-00 00:00:00 2026 0 0 13 str. iss. 12, art. 6079 Vol. 16 2026 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 615.82/.84 2076-3417 10.3390/app16126079 281888259 applsci-16-06079.pdf applsci-16-06079.pdf 1 90B8232BC91574ECDDE0FF4DD97195D9 b362b778a74c7047b55a032288835179bbb0b3c5b002e92037aa7b57bb83e127 89c81dc5-6a1f-11f1-9b0d-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=235808 https://www.mdpi.com/2076-3417/16/12/6079 1 a121d794-8fcd-11f1-9b0d-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=243888 Zdravstvena fakulteta Medicinska fakulteta 0 0 0