20.500.12556/RUL-183078 Acute ischemic stroke trends in Slovenia, 2015-2022 declining admissions, rising reperfusion, uneven gains Introduction: We assessed nationwide trends in administratively identified ischaemic stroke admissions, procedures, secondary prevention, and outcomes in Slovenia using linked national datasets in the absence of a dedicated stroke registry. Methods: We conducted a nationwide longitudinal analysis of adult hospital admissions captured in linked administrative databases between 2015 and 2022. We report crude index-admission rates, acute procedures (intravenous thrombolysis [IVT], mechanical thrombectomy [MT], carotid thromboendarterectomy [CEA], carotid artery angioplasty with stenting [CAS]), discharge secondary-prevention prescriptions, and time-to-death analyses with a maximum follow-up of 5 years. Results: We included 16,839 unique index patients (median age 74 years; 54% male). Admissions peaked in 2017 (2169) and crude rates decreased from 105 to 99 per 100,000 residents by 2022. Revascularisation increased (IVT 6.2% to 15%, MT 5.4% to 9.5%, CEA 9.1% to 14%), length of stay decreased, and discharge prevention therapy improved. Five-year mortality was higher with age and comorbidity and lower among patients receiving IVT and several secondary-prevention therapies. Care pathways differed by stroke aetiology; women were older and men underwent more CAS and CEA, while IVT and MT were similar. Conclusion: Crude admissions declined modestly while reperfusion and prevention improved, but the magnitude and pattern of improvement differed by care domain and patient subgroup, supporting continued monitoring and the development of a national stroke registry. ischaemic stroke intravenous thrombolysis mechanical thrombectomy carotid endarterectomy thromboendarterectomy Slovenia health diseases Slovenija zdravje bolezni kap zdravljenje trendi true false true Angleški jezik Slovenski jezik Članek v reviji 2026-06-04 05:16:23 2026-06-04 09:18:05 2026-07-09 08:43:39 0000-00-00 00:00:00 2026 0 0 8 str. iss. 7, art. 108668 Vol. 35 Jul. 2026 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 616.12 1052-3057 10.1016/j.jstrokecerebrovasdis.2026.108668 279993091 RAZ_Furlan_Tjasa_2026.pdf RAZ_Furlan_Tjasa_2026.pdf 1 42DC3C2DC3720A9070F1C31BFD6F32B0 f937f6f84a45765d29cf256aaac0d18ac9dcd82b3cdf8ddd06c643dcbaa61758 3fe6cbe6-5fe6-11f1-b0ab-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=234939 https://www.sciencedirect.com/science/article/pii/S105230572600131X 0 e86f6106-5ff0-11f1-b0ab-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=234946 Medicinska fakulteta Fakulteta za elektrotehniko Fakulteta za šport Ekonomska fakulteta 0 0 0