20.500.12556/RUL-183053 Vpliv aerobne vadbe med zdravljenjem raka dojke na kakovost življenja in utrujenost bolnic - pregled literature diplomsko delo The effect of aerobic exercise during breast cancer treatment on quality of life and fatigue in patients - literature review diploma work Uvod: Rak dojke je najpogostejši rak pri ženskah, zdravljenje pa je pogosto povezano z izrazito utrujenostjo ter zmanjšano kakovostjo življenja. Telesna vadba se uveljavlja kot ena izmed pomembnih nefarmakoloških intervencij za obvladovanje teh težav, vendar učinki aerobne vadbe med zdravljenjem še niso povsem enotni. Namen: Namen diplomskega dela je bil pregledati obstoječe raziskave o vplivu aerobne vadbe med zdravljenjem raka dojke na z rakom povezano utrujenost in kakovost življenja ter opredeliti značilnosti učinkovitih vadbenih pristopov. Metode dela: Izveden je bil pregled literature v podatkovni zbirki PubMed. Vključene so bile randomizirane nadzorovane raziskave, objavljene v zadnjih desetih letih, ki so proučevale učinke aerobne vadbe na utrujenost in/ali kakovost življenja pri bolnicah z rakom dojke med aktivnim zdravljenjem. Metodološka kakovost raziskav je bila ocenjena z lestvico PEDro. Rezultati: V končno analizo je bilo vključenih sedem raziskav. Programi aerobne vadbe so trajali od osem tednov do 64 tednov , najpogosteje 12 - 20 tednov. Vadba se je najpogosteje izvajala na tekalni stezi, sobnem kolesu ali v obliki hoje. Intervencije, pri katerih so ugotovili ugoden vpliv na utrujenost ali kakovost življenja, so najpogosteje vključevale vadbo 2- do 3-krat tedensko v trajanju 20–60 min pri zmerni do visoki intenzivnosti (50–95 % maksimalnega srčnega utripa), pogosto v obliki intervalne vadbe ali z načrtovanim postopnim stopnjevanjem obremenitve. Statistično značilen pozitiven vpliv aerobne vadbe na z rakom povezano utrujenost je bil ugotovljen v treh od petih raziskav, kjer je vadba zmanjšala utrujenost ali preprečila njeno poslabšanje med zdravljenjem, medtem ko v dveh raziskavah statistično značilnih razlik niso ugotovili. Pri kakovosti življenja so bili rezultati manj enotni. Statistično značilno izboljšanje globalne kakovosti življenja je bilo ugotovljeno v dveh raziskavah, medtem ko so v več raziskavah poročali o izboljšanju posameznih domen kakovosti življenja, predvsem telesnega, čustvenega in funkcionalnega delovanja. Razprava in zaključek: Aerobna vadba predstavlja varen in koristen del podporne onkološke obravnave ter lahko prispeva k ohranjanju funkcionalnosti in počutja bolnic med zdravljenjem raka dojke. Kot klinično smiselna se kaže redna aerobna vadba zmerne ali visoke intenzivnosti s postopnim stopnjevanjem obremenitve, ki se izvaja večkrat tedensko in je individualno prilagojena zmogljivosti posameznice ter poteku zdravljenja. Introduction: Breast cancer is the most common cancer among women, and its treatment is often associated with pronounced fatigue and reduced quality of life. Physical exercise has emerged as an important non-pharmacological intervention for managing these symptoms; however, the effects of aerobic exercise during active treatment are not yet entirely consistent. Purpose: The aim of this diploma thesis was to review existing studies on the effects of aerobic exercise during breast cancer treatment on cancer-related fatigue and quality of life and to identify the characteristics of effective exercise interventions. Methods: A literature review was conducted using the PubMed database. Randomised controlled trials published within the last ten years were included if they investigated the effects of aerobic exercise on fatigue and/or quality of life in women with breast cancer during active treatment. Methodological quality was assessed using the PEDro scale. Results: Seven studies were included in the final analysis. Aerobic exercise programmes lasted from eight weeks to 64 weeks, most commonly 12–20 weeks. Exercise was most frequently performed on a treadmill, stationary bicycle, or in the form of walking. Interventions that demonstrated a beneficial effect on fatigue or quality of life most often included exercise performed 2–3 times per week for 20–60 minutes at moderate to high intensity (50–95% of maximal heart rate), often in the form of interval training or with planned gradual progression of workload. A statistically significant positive effect of aerobic exercise on cancer-related fatigue was found in three of five studies, where exercise reduced fatigue or prevented its worsening during treatment, whereas two studies did not report statistically significant differences. The results regarding quality of life were less consistent. A statistically significant improvement in global quality of life was reported in two studies, while several studies reported improvements in specific domains of quality of life, particularly physical, emotional, and functional functioning. Discussion and conclusion: Aerobic exercise represents a safe and beneficial component of supportive oncological care and may contribute to maintaining functional capacity and well-being in women undergoing breast cancer treatment. Regular aerobic exercise of moderate to high intensity with gradual progression of workload appears to be clinically meaningful, particularly when performed several times per week and individually adapted to the patient’s capacity and treatment course. diplomska dela fizioterapija rak dojke aerobna vadba z rakom povezana utrujenost kakovost življenja onkološko zdravljenje diploma theses physiotherapy breast cancer aerobic exercise cancer-related fatigue quality of life oncological treatment true false false [A. Vindiš] Slovenski jezik Angleški jezik Diplomsko delo/naloga 2026-06-03 07:45:36 2026-06-03 07:45:51 2026-06-04 04:11:11 0000-00-00 00:00:00 2026 0 Ljubljana 0 Ljubljana VIII, 32 str. 0000-00-00 NiDoloceno NiDoloceno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 615.8 159971 280217347 59180.pdf 59180.pdf 1 2512CC6419D08C32BD43257B588F7D52 d377f0132b16b1de19da60c9a91a6089019f303568bafc28ff9b83e2a96857eb 1e4c042b-5f0f-11f1-b0ab-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=234865 Zdravstvena fakulteta 0 0 0