20.500.12556/RUL-182700 The effect of artificial gravity on the outcome of a two-week resistance vibration exercise programme BRAVE study We evaluated the feasibility and efficacy of a 2-week training programme comprising resistance vibration exercise (RVE) without and with artificial gravity (AG). Participants (n = 24) were divided into three groups: (i) URVE: upright loaded squat exercise; (ii) HRVE: horizontal loaded squat exercise; and (iii) AGRVE: loaded squat exercise conducted on a short-arm human centrifuge. All participants followed the same protocol and were exposed to the same ground reaction force, whilst performing exercise comprising bilateral squats, triple extension squats and single/bilateral calf raises. Before and after the 2-week training period, we measured thigh and calf muscle strength with isokinetic dynamometry, muscular power with a jump test, volume with functional muscle magnetic resonance imaging, and body composition with dual-energy X-ray absorptiometry. All groups showed significant improvements in eight-repetition maximum squat strength (P < 0.0001, G > 0.80), whilst only the AGRVE group demonstrated a small effect in jump height (G=0.26). The AGRVE group significantly increased knee extension and flexion maximum voluntary contraction (MVC), with no comparable changes in the HRVE or URVE groups. The AGRVE group increased total thigh muscle volume (P = 0.03), with notable hypertrophy in the vastus medialis, semitendinosus, and vastus intermedius muscles. These findings demonstrate that AGRVE is significantly superior to HRVE and URVE in enhancing knee MVC and thigh muscle volume, thus indicating that artificial gravity improves the outcome of resistance vibration exercise in ambulatory participants. exercise physiology artificial gravity muscle strength resistance vibration exercise umetna gravitacija mišična moč telovadba fiziologija true false true Angleški jezik Slovenski jezik Članek v reviji 2026-05-21 09:10:02 2026-05-21 09:10:12 2026-05-23 04:41:55 0000-00-00 00:00:00 2026 0 0 Str. 1165-1180 iss. 3 Vol. 111 Mar. 2026 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 612 1469-445X 10.1113/EP093066 260931331 Experimental_Physiology_-_2025_-_Mekjavic_-_The_effect_of_artificial_gravity_on_the_outcome_of_a_two‐week_resistance.pdf Experimental_Physiology_-_2025_-_Mekjavic_-_The_effect_of_artificial_gravity_on_the_outcome_of_a_two‐week_resistance.pdf 1 FC33034BAC6E81C828C8F51AB0E6E708 265f052002801a5ecc8dfcd0602f9b9152f4df7f7340ee31d352653e2671b8d9 4ed03075-55b6-11f1-b0ab-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=234297 https://physoc.onlinelibrary.wiley.com/doi/10.1113/EP093066 1 ca839af1-54e3-11f1-b0ab-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=234179 Fakulteta za šport Medicinska fakulteta 0 0 0