20.500.12556/RUL-182658 Chromatic visual evoked potentials a review of physiology, methods and clinical applications Objective assessment of the visual system can be performed electrophysiologically using the visual evoked potential (VEP). In many clinical circumstances, this is performed using high contrast achromatic patterns or diffuse flash stimuli. These methods are clinically valuable but they may only assess a subset of possible physiological circuitries within the visual system, particularly those involved in achromatic (luminance) processing. The use of chromatic VEPs (cVEPs) in addition to standard VEPs can inform us of the function or dysfunction of chromatic pathways. The chromatic VEP has been well studied in human health and disease. Yet, to date our knowledge of their underlying mechanisms and applications remains limited. This likely reflects a heterogeneity in the methodology, analysis and conclusions of different works, which leads to ambiguity in their clinical use. This review sought to identify the primary methodologies employed for recording cVEPs. Furthermore cVEP maturation and application in understanding the function of the chromatic system under healthy and diseased conditions are reviewed. We first briefly describe the physiology of normal colour vision, before describing the methodologies and historical developments which have led to our understanding of cVEPs. We thereafter describe the expected maturation of the cVEP, followed by reviewing their application in several disorders: congenital colour vision deficiencies, retinal disease, glaucoma, optic nerve and neurological disorders, diabetes, amblyopia and dyslexia. We finalise the review with recommendations for testing and future directions. chromatic chromatic VEP colo*r electrophysiology VEP visual evoked potentials kromatsko kromatsko VEP barva elektrofiziologija vizualno evocirani potenciali true false true Angleški jezik Ni določen Članek v reviji 2026-05-20 11:33:14 2026-05-20 11:33:22 2026-07-16 12:08:22 0000-00-00 00:00:00 2024 0 0 24 str. art. 101272 Vol. 101 2024 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 617.7 1873-1635 10.1016/j.preteyeres.2024.101272 197909251 RAZ_Marmoy_Oliver_R._2024.pdf RAZ_Marmoy_Oliver_R._2024.pdf 1 C0CD2D70A291CCCB97BE0A7E2B8B0AAC d5da5b099fd0131e989e3937db1ccf9af784668c098b70b08adb7f9c7a9abe2f 28e84176-542f-11f1-b0ab-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=234120 https://www.sciencedirect.com/science/article/pii/S1350946224000375?ref=pdf_download&fr=RR-2&rr=88ee811419b05b81 1 9fe98a9b-542e-11f1-b0ab-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=234117 Medicinska fakulteta 0 0 0