20.500.12556/RUL-182259 Environmental toxicity of selected aminoglycoside antibiotics to Lemna minor Aminoglycoside antibiotics (AGs) are widely used in human and veterinary medicine. After administration, AGs undergo minimal metabolism and are excreted in their active form, contributing to their presence in the envi ronment. The aim of our study was to determine the ecotoxicological characteristics of five AGs commonly used in human and veterinary medicine: gentamicin, neomycin, spectinomycin, streptomycin and dihydros treptomycin. Their effects on growth and chlorophyll synthesis were investigated under laboratory conditions using the model plant organism Lemna minor. For each AG, logarithmic dilution was performed to yield test solutions with concentrations ranging from 0.001 to 100 mg/L. In the growth inhibition test, low concentrations of spectinomycin and streptomycin stimulated the growth of Lemna minor. The lowest EC₅₀ values, indicating the greatest toxicity, were detected for gentamicin and dihydrostreptomycin, at 0.397 and 0.625 mg/L, respectively. The results of the chlorophyll synthesis test revealed that neomycin and gentamicin had the lowest EC50 values, at 45.33 and 56.01 mg/L, respectively. The other AGs tested did not notably affect chlorophyll synthesis. aminoglycoside antibiotics ecotoxicity Lemna minor growth inhibition chlorophyll synthesis true false true Angleški jezik Angleški jezik Članek v reviji 2026-05-05 13:59:11 2026-05-05 13:59:16 2026-05-06 04:29:09 0000-00-00 00:00:00 2026 0 0 18 str. Vol. 22, art. 101186 May 2026 0000-00-00 Zaloznikova Objavljeno apc 0000-00-00 0000-00-00 2026-05-01 614 2772-4166 10.1016/j.hazadv.2026.101186 276777987 Environmental-Snoj.pdf Environmental-Snoj.pdf 1 C83873E686E955E18EAB12C219150701 6fa9ae167089fefb768dd11502c5c4248be19347deb3d27ddfef42c33128d68c b79e2fe5-487a-11f1-b0ab-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=233358 https://www.sciencedirect.com/science/article/pii/S2772416626001853?via%3Dihub Odprti dostop 1 8f8ec22f-4879-11f1-b0ab-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=233357 Veterinarska fakulteta 0 0 0