20.500.12556/RUL-181833 Synthesis of (S)-4-benzyl-3-butyl-1-(2-cycloheptylethyl)imidazolidine LiAlH$_4$ reduction of tert-butyl (S)-butyl(1-((2-cycloheptylethyl)amino)-1-oxo-3-phenylpropan-2-yl)carbamate (1) gave imidazolidine 2, while treatment with lithium diisopropylamide furnished the β-elimination product, cinnamamide 3. Both products were fully characterized. Reductive cyclization of N-alkylated-N-Boc-protected amino acid amides with LiAlH$_4$ may be a viable synthetic method for trisubstituted chiral imidazolidines. LiAlH$_4$ amide reduction imidazolidine β-elimination cinnamamide LiAlH$_4$ redukcija amida imidazolidin β-eliminacija ciamamid true false true Angleški jezik Slovenski jezik Članek v reviji 2026-04-16 13:55:57 2026-04-16 13:55:58 2026-04-17 04:53:17 0000-00-00 00:00:00 2026 0 0 6 str. iss. 2, art. M2166 Vol. 2026 Apr. 2026 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 547.78 1422-8599 10.3390/M2166 275463683 RAZ_Schweiger_Matevz_2026.pdf RAZ_Schweiger_Matevz_2026.pdf 1 2070C3B75364BA32E8B7FEA2189C0DBF 99ca5a584e59d2e397b58218eee830b420fbf01afa2f121c5552f5e75b585c6f 7de7e7a7-398b-11f1-b0ab-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=232577 https://www.mdpi.com/1422-8599/2026/2/M2166 1 01c9a96f-398b-11f1-b0ab-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=232576 Fakulteta za kemijo in kemijsko tehnologijo 0 0 0