20.500.12556/RUL-175453 Bridging spectroscopy and advanced molecular orientation analysis with new 4＋ angle polarization toolbox in Quasar Anisotropy plays a critical role in governing the mechanical, thermal, electrical, magnetic, and optical properties of materials, influencing their behavior across diverse applications. Probing and quantifying this directional dependence is crucial for advancing materials science and biomedical research, as it provides a deeper understanding of structural orientations at the molecular level, encompassing both scientific and industrial benefits. This study introduces the ‘‘4+ Angle Polarization’’ widget, an innovative extension to the open-source Quasar platform (https://quasar.codes/), tailored for advanced multiple-angle polarization analysis. This toolbox enables precise in-plane molecular orientation analysis of complex microspectroscopic datasets through a streamlined workflow. Using polarized Fourier transform infrared (p-FTIR) spectroscopy, we demonstrate its versatility across various sample types, including polylactic acid (PLA) organic crystals, murine cortical bone, and human osteons. By overcoming the limitations of traditional two-angle methods, the widget significantly enhances the accuracy of structural and orientational analysis. This novel analytical tool expands the potential of multiple-angle p-FTIR techniques into advanced characterization of structural anisotropy in heterogeneous systems, providing transformative insights for materials characterization, biomedical imaging and beyond. molecular orientation chemical imaging Quasar 4+ angle polarization widget vector map polylactic acid PLA cortical bone human osteon orientacija molekul molekularna orientacija kemijsko slikanje vektorski zemljevid polilaktična kislina PLA kortikalna kost človeški osteon true false true Angleški jezik Slovenski jezik Članek v reviji 2025-10-28 09:25:45 2025-10-28 09:25:46 2025-12-11 03:45:38 0000-00-00 00:00:00 2025 0 0 16 str. Št. 110573 Vol. 196 Sep. 2025 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 004: 543.42 0010-4825 10.1016/j.compbiomed.2025.110573 243360259 RAZ_Gassner_Callum_2025.pdf RAZ_Gassner_Callum_2025.pdf 1 50BE3BD654C657D76635ECDE85F8DC48 a54ab455e9fd4a30e5779b5cbeb86f2ee8847ad975b77c9a69827ee584aa9ef8 c75ec074-b3dd-11f0-9328-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=221009 https://www.sciencedirect.com/science/article/pii/S0010482525009242?via%3Dihub 1 681f52c3-b3d7-11f0-9328-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=221002 Fakulteta za računalništvo in informatiko 0 0 0