20.500.12556/RUL-175213 Antioxidant strategies for age-related oxidative damage in dogs This review examines the effects of oxidative stress on the aging process in canines, focusing on the role of antioxidants in the prevention of age-related diseases. Oxidative stress is caused by an imbalance between the production of free radicals and the body’s antioxidant defenses, resulting in damage to cell structures. Dogs, especially older animals, are particularly susceptible to such damage, which contributes to the development of cognitive impairment, chronic disease and a reduced quality of life. Antioxidants such as vitamins C and E, coenzyme Q10 and polyphenols play an important role in neutralizing free radicals and mitigating oxidative damage. Various studies confirm that these antioxidants can improve overall health, slow cognitive decline and reduce the risk of diseases such as osteoarthritis, cancer and heart disease. The results suggest that an appropriate diet supplemented with antioxidants can significantly contribute to a better quality of life for dogs. However, given that some studies report limited or no effects, additional long-term clinical trials are warranted to validate the reproducibility and degree of presented benefits. oxidative stress antioxidants aging dogs cognitive dysfunction true false true Angleški jezik Ni določen Članek v reviji 2025-10-22 04:34:51 2025-11-20 13:31:41 2025-12-06 04:06:55 0000-00-00 00:00:00 2025 0 0 22 str. iss. 10, art. 962 Vol. 12 2025 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 636.09:616 2306-7381 10.3390/vetsci12100962 252941827 Antioxidant_strategies-Nemec_Svete.pdf Antioxidant_strategies-Nemec_Svete.pdf 1 36BB1385031E01CF7A002C2E14141DB3 a7b4b1cdc92a82eab6eb8c9f31e557024b9220abbbb3af67dad3a8b6a7a02d88 789963cf-afec-11f0-9328-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=220717 https://www.mdpi.com/2306-7381/12/10/962 1 6b41f823-aeef-11f0-9328-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=220547 Zdravstvena fakulteta Veterinarska fakulteta 0 0 0