20.500.12556/RUL-173747 Učinki probiotikov na zdravje črevesja Effects of probiotics on gut health Probiotiki so živi mikroorganizmi, ki lahko, če jih zaužijemo v zadostnih količinah, ugodno vplivajo na zdravje gostitelja. Zdravje črevesja je tesno povezano z načinom življenja. Temeljnega pomena za ohranjanje zdravja gostitelja je tudi črevesna mikrobiota. Njeno sestavo oblikujejo gostiteljski in okoljski dejavniki. Namen te naloge je bil raziskati učinke probiotikov na zdravje črevesja, s poudarkom na njihovih mehanizmih delovanja, interakciji z mikrobioto in imunskim sistemom ter kliničnih učinkih pri različnih gastrointestinalnih boleznih. Analizirani so bili tudi prebiotiki, sinbiotiki in najpogosteje uporabljeni probiotični sevi ter tveganja njihove uporabe. Probiotiki predstavljajo eno izmed možnosti za obnovitev porušenega mikrobnega ravnovesja, disbioze, ker je tista povezana z številnimi zdravstvenimi težavami. Ugotovljeno je bilo, da probiotiki lahko prispevajo k obnovi črevesne mikrobiote po antibiotični terapiji, lajšajo simptome sindroma razdražljivega črevesja, pomagajo pri obvladovanju vnetnih črevesnih bolezni in celo zmanjšujejo tveganje za razvoj določenih vrst raka in prekomerne telesne teže. Kljub obetavnim rezultatom pa njihova učinkovitost ostaja odvisna od specifičnih sevov, odmerka in stanja posameznika. Nadaljnje raziskave so nujne za standardizacijo terapevtskih pristopov in oceno dolgoročne varnosti. Probiotics are living microorganisms that, if consumed in sufficient quantities, can have a pleasant effect on the host's health. Gut health is closely related to lifestyle. The intestinal microbiota is also of fundamental importance for maintaining the health of the host. Its composition is shaped by hospitality and environmental factors. The purpose of this assignment was to investigate the effects of probiotics on intestinal health, with an emphasis on their mechanisms of action, interaction with microbiota and the immune system, and clinical effects in various gastrointestinal diseases. Prebiotics, synbiotics and the most commonly used probiotic strains and the risks of their use were also analyzed. Probiotics represent one of the options for restoring the broken microbial balance, dysbiosis, because it is associated with many health problems. It was found that probiotics can easily contribute to the restoration of intestinal microbiota after antibiotic therapy, relieve the symptoms of irritable bowel syndrome, help in the management of inflammatory bowel diseases and even reduce the risk of developing certain types of cancer and excess body weight. Despite the promising results, their effectiveness remains dependent on the specific strains, dosage and condition of the individual. Further research is necessary to standardize therapeutic approaches and assess long-term safety. črevesna mikrobiota probiotiki mehanizmi delovanja zdravje gastrointestinalni trakt patogeni sev črevesne bolezni gut microbiota probiotics mechanisms of action health gastrointestinal tract pathogens strain intestinal diseases true false false Slovenski jezik Angleški jezik Diplomsko delo/naloga 2025-09-21 07:17:25 2025-09-21 07:17:29 2025-10-11 04:06:46 0000-00-00 00:00:00 2025 0 0 0000-00-00 NiDoloceno NiDoloceno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 265257 249770499 53347.pdf 53347.pdf 1 34312C45A4AB4474EE36FB29CB2E85DE 7838067a4a69ed738c70d3905d03fb18b180612de95a4d5ee7a2c3abcc9d22d8 16708aa7-96aa-11f0-9328-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=218399 Biotehniška fakulteta 0 0 0