20.500.12556/RUL-169988 Application of (aza)quinolizinyl-3-diazonium tetrafluoroborates in photocatalytic sulfanylation and in fluorescent labeling of proteins Photocatalytic sulfanylations of (aza)quinolizine diazonium salts with disulfides and thiols, including N-Boc-protected cysteine and cystine esters, gave the corresponding fluorescent sulfanylation products in 25–85 % yield. Photocatalytic cycle was proposed for the sulfanylation with disulfides using diazonium salts as heteroaryl radical sources. Two representative diazonium salts were evaluated as bioconjugation reagents for fluorescent labeling of proteins using bovine serum albumin (BSA) as a model protein and targeting cysteine residues, and the results showed their applicability in fluorescent labeling under photocatalytic conditions. sulfanylation arylation quinolizines azaquinolizines photoredox catalysis diazonium salts bioconjugation fluorescent labeling proteins sulfaniliranje ariliranje kinolizini azakinolizini fotoredoks kataliza diazonijeve soli biokonjugacija fluorescentno označevanje proteini true false true Angleški jezik Slovenski jezik Članek v reviji 2025-07-01 10:27:36 2025-07-01 10:27:37 2026-06-30 04:00:52 0000-00-00 00:00:00 2025 0 0 17 str. Vol. 163, art. 108686 Aug. 2025 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 547.83:544.526.5:577.112 0045-2068 10.1016/j.bioorg.2025.108686 240849155 1-s2.0-S0045206825005668-main.pdf 1-s2.0-S0045206825005668-main.pdf 1 7D5F5D32141E86CD7F49B2B9D9685DCD 9fd983ec6d38bac78750149b11a6dd9ff1cb25c711700136dd793f2e6c40e79c cf2845b7-739f-11f1-9b0d-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=236595 https://www.sciencedirect.com/science/article/pii/S0045206825005668 1 5b0d210b-5653-11f0-b232-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=211881 Fakulteta za kemijo in kemijsko tehnologijo 0 0 0