20.500.12556/RUL-169062 Anisotropic DLVO-like interaction for charge patchiness in colloids and proteins The behaviour and stability of soft and biological matter depend significantly on electrostatic interactions, as particles such as proteins and colloids acquire a charge when dispersed in an electrolytic solution. A typical simplification used to understand bulk phenomena involving electrostatic interactions is the isotropy of the charge on the particles. However, whether arising naturally or by synthesis, charge distributions are often inhomogeneous, leading to an intricate particle-particle interaction landscape and complex assembly phenomena. The fundamental complexity of these interactions gives rise to models based on distinct assumptions and varying degrees of simplifications which can blur the line between genuine physical behaviour and artefacts arising from the choice of a particular electrostatic model. Building upon the widely-used linearized Poisson-Boltzmann theory, we propose a theoretical framework that – by bridging different models – provides a robust DLVO-like description of electrostatic interactions between inhomogeneously charged particles. By matching solely the single-particle properties of two different mean-field models, we find a quantitative agreement between the pair interaction energies over a wide range of system parameters. Our work identifies a strategy to merge different models of inhomogeneously charged particles and paves the way to a reliable, accurate, and computationally affordable description of their interactions. biological physics electrostatic interactions biofizika elektrostatske interakcije true false true Angleški jezik Slovenski jezik Članek v reviji 2025-05-09 10:37:15 2025-05-09 10:37:16 2025-05-10 04:10:33 0000-00-00 00:00:00 2025 0 0 9 str. art. no. ǂ4277 Vol. 16 May 2025 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 577.3:537.2 2041-1723 10.1038/s41467-025-58991-0 235331331 s41467-025-58991-0.pdf s41467-025-58991-0.pdf 1 535C42556CB45E1844FA61E6BE54C15A a79372f152c366b8a63b9924ddf02ff0761aa52f59e97a39ed86760bcc38c317 019e03ca-2cb0-11f0-b232-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=210200 https://www.nature.com/articles/s41467-025-58991-0 0 17b680bb-2cb0-11f0-b232-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=210201 Fakulteta za matematiko in fiziko 0 0 0