20.500.12556/RUL-169059 Comparative analysis of Anti-Müllerian hormone concentration in two indigenous Slovenian sheep breeds Anti-Müllerian hormone (AMH), produced only by granulosa cells, is a biomarker for ovarian reserve in sheep. This study compared AMH levels in two Slovenian breeds: Istrska pramenka (IP), a seasonal breeder, and Jezersko–Solčava (JS), which reproduces year-round. Blood serum samples from 78 sheep were analyzed during the estrus period using an ovine AMH ELISA. JS sheep were grouped by age (1–3, 4–6, ≥ 7 years), while the majority of IP sheep were ≥7 years. AMH levels differed significantly between breeds (p < 0.001), with JS sheep showing higher concentrations. No age-related differences were found within the JS breed (p = 0.752), but JS sheep ≥ 7 years had higher AMH than IP sheep of the same age (p < 0.001). AMH levels were also higher in ewes lambing two lambs (p < 0.001) and were positively correlated with litter size, particularly in the JS sheep ≥ 7 years (p < 0.001). These findings suggest AMH is a useful fertility marker in sheep, although breed-specific reference values are essential for an accurate interpretation. The study highlights the influence of breed and age on AMH levels and its potential role in predicting reproductive performance. anti-Müllerian hormone reproductive activity Jezersko–Solčava breed Istrska pramenka breed ovarian reserve prolificacy fertility sheep true false true Angleški jezik Ni določen Članek v reviji 2025-05-09 09:10:16 2025-05-09 09:10:23 2025-10-17 13:10:49 0000-00-00 00:00:00 2025 0 0 9 str. iss. 9, art. 1332 Vol. 15 2025 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 636.3:618 2076-2615 10.3390/ani15091332 235299331 comparative-Sterbenc.pdf comparative-Sterbenc.pdf 1 DBF5150955B93D824D6609B632038759 2bd7c34cf8161c15bdf8ecf18c980edc433ef92815d9b1b5cf1e047cbef54fca 0e0b0300-a8f0-11f0-9328-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=220082 https://www.mdpi.com/2076-2615/15/9/1332 prosti dostop 1 79fc1134-2ca3-11f0-b232-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=210194 Veterinarska fakulteta 0 0 0