20.500.12556/RUL-169048 Closed-loop control of anesthesia using two-degrees-of-freedom control with a target-controlled infusion algorithm This article proposes a new closed-loop control method to induce and maintain a desired depth of hypnosis during total intravenous anesthesia. The method utilizes two-degreesof-freedom control, with propofol infusion rate as the input and bispectral index (BIS) as the output. A target-controlled infusion (TCI) algorithm called STANPUMP is used as the feedforward action to achieve the desired BIS response, and a feedback controller based on a Kalman filter deals with model uncertainties. Adding a TCI algorithm as the feedforward action improves the time-to-target and enhances patient safety. This is because it allows for a seamless transition to open-loop control if needed. closed-loop control anesthesia bispectral index (BIS) target-controlled infusion (TCI) two-degrees-of-freedom control (2 DoF) model predictive control (MPC) STANPUMP zaprtozančno vodenje anestezija bispektralni indeks ciljno krmiljena infuzija regulacija s krmilnim delom prediktivno vodenje STANPUMP true false true Angleški jezik Slovenski jezik Članek v reviji 2025-05-08 13:44:38 2025-05-08 13:44:43 2025-05-09 04:28:33 0000-00-00 00:00:00 2025 0 0 Str. 367-372 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 681.5 2405-8963 10.1016/j.ifacol.2025.03.063 234806787 234805251 1-s2.0-S2405896325002800-main.pdf 1-s2.0-S2405896325002800-main.pdf 1 8EBDD209F3E53A84825492219C727DE7 3bcf957fb95730f3e44b83f089a340287674211bae07c93ec7bd4395c03fe971 fdd6bd17-2c00-11f0-b232-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=210179 https://www.sciencedirect.com/science/article/pii/S2405896325002800 1 a3247429-2c00-11f0-b232-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=210178 Fakulteta za elektrotehniko 0 0 0