20.500.12556/RUL-166706 A pilot study on the age-dependent, biomechanical properties of longitudinal ligaments in the human cervical spine The cervical spine ligaments, including the anterior longitudinal ligament (ALL) and posterior longitudinal ligament (PLL), play a key role in maintaining spinal stability by limiting excessive movements. This study investigates how ageing affects the mechanical properties of these ligaments. We analysed 33 samples from 12 human cervical spines (15 ALL, 18 PLL), averaging data from the same donors for independent analysis, resulting in 18 final samples (8 ALL, 10 PLL). To explore age-related changes, we classified the samples into two groups—below and above 50 years old—aligning with the peak incidence of major musculoskeletal disorders. The investigation concentrated on the effects of age on four mechanical parameters of the uniaxial stress–stretch curve: initial tangent stiffness (EO), maximum tangent stiffness (Em), ultimate stress (Pu) and ultimate stretch. When the age effect is neglected, then the behaviours of both the ALL and PLL appeared similar. However, when introducing age as a variable into the context of the ALL and PLL, statistically significant differences became evident. The findings underscored a reduction in maximum tangent stiffness (p-value = 0.0147), ultimate stress (p-value = 0.0009), and ultimate stretch (p-value = 0.0024) when the ALL and PLL were grouped under and above 50 years as a consequence of ageing. human cervical spine ligament tension test age-related changes biomechanics mechanobiology osteoarthritis true false true Angleški jezik Angleški jezik Članek v reviji 2025-01-22 10:48:53 2025-01-22 10:48:58 2025-01-23 03:54:05 0000-00-00 00:00:00 2025 0 0 13 str. no. 1, [art. no.] 61 Vol. 12 2025 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 60:531/533:61 2306-5354 10.3390/bioengineering12010061 223440131 Singh_..._A_pilot_study.pdf Singh_..._A_pilot_study.pdf 1 61C48FDDA87B6B79D7DCAB4FC17FC243 0541d458fd790b544a2fbfaf8ace0e6760d6bfd89de49c67b621b370905f0fc7 e3064df1-d8a5-11ef-b232-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=198517 https://www.mdpi.com/2306-5354/12/1/61 1 51a24729-d8a5-11ef-b232-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=198516 Fakulteta za strojništvo 0 0 0