20.500.12556/RUL-166313 Phenolic profile and antioxidant capacity of invasive Solidago canadensis L. potential applications in phytopharmacy Canadian goldenrod (Solidago canadensis L.), an invasive plant in Europe, is known for its allelopathic activity and is rich in bioactive compounds like flavonoids and phenolic acids, with significant pharmacological potential. This study presents the LC-MS phenolic profiles of leaf and flower extracts from S. canadensis, an invasive alien plant in the Istria region (Croatia). Total phenolics (TP) (45.78–110.68 mg GAE/g DW) and non-flavonoids (TNF) (28.38–72.20 mg GAE/g DW) were found to be more abundant in ethanolic than in methanolic extracts. The antioxidant capacity (AC), as measured by ABTS, DPPH, and FRAP assays, was higher in flower extracts compared to leaf extracts. A non-targeted metabolomics approach was used, and 41 phenolic compounds in leaves and 36 in flowers were identified, with hydroxycinnamic acids and flavonols being the most abundant. 5-caffeoylquinic acid was quantitatively predominant in the leaf extracts, while quercetin-3-rutinoside dominated the flower extracts. Five leaf-specific compounds were identified (dicaffeoylquinic acid 2, 4-p-coumaroylquinic acid 1, p-hydroxybenzoic acid, quercetin-3-rhamnoside, and quercetin acetylhexoside 1), suggesting targeted extraction for different pharmacological applications. This study highlights the therapeutic potential of S. canadensis and underscores the need for further research on the bioavailability, efficacy, and safety of its compounds, potentially transforming this ecological threat into a valuable resource for drug development. Canadian goldenrod flower invasive plants leaf plant extracts kanadska zlata rozga cvetovi invazivne rastline listi rastlinski izvlečki true false true Angleški jezik Slovenski jezik Članek v reviji 2025-01-07 11:28:47 2025-01-07 11:28:52 2025-01-08 04:00:00 0000-00-00 00:00:00 2025 0 0 17 str. iss. 1, art. 44 Vol. 14 2024 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 63 2223-7747 10.3390/plants14010044 221010435 Phenolic_Profile_and_Antioxidant_Capaci...pdf Phenolic_Profile_and_Antioxidant_Capaci...pdf 1 CE0FEA6E2868B5A3975E2D507A20212B 09d58d0c0d2fa9ae2e62fd9000f1f4c5af351dd84bf2abab1b85a0bbe26486df f7b20156-cce1-11ef-b232-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=197841 https://www.mdpi.com/2223-7747/14/1/44 1 7c426db5-cce1-11ef-b232-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=197840 Biotehniška fakulteta 0 0 0