20.500.12556/RUL-164874 Combined effects of cyclic heat stress, dietary induced oxidative stress and different levels of antioxidant on gut fermentation activity and mucosal morphology in broiler chickens The gastrointestinal tract of broilers is susceptible to oxidative stress induced by heat stress (HS) and diet, which can be mitigated by the supply of exogenous vitamins and antioxidants. The aim of this study was to compare the extent of the effects of cyclic HS, and high levels of polyunsaturated fatty acids (PUFA) (HP) on gut health. It also aimed to investigate whether additional supplementation with vitamins E, C and selenium (HA) is required to support gut health under these conditions. In the present study, 192 one-day-old male Ross 308 broilers were randomly divided into eight experimental groups. Exposure to HS and HP significantly (p < 0.001) decreased villus height and villus-to-crypt ratio in the duodenum, while no differences were observed in the jejunum and ileum. In addition, oxidative stress in the liver, indicated by increased malondialdehyde (MDA) levels, was increased in the HP groups (p < 0.0001), while the HA groups had a positive effect on lowering MDA levels. The results confirm that cyclic HS and HP induce oxidative stress that damages the structure of intestinal morphology and that supplementation with HA could be a potential approach to mitigate the negative effects of these stressors. cyclic heat stress polyunsaturated fatty acids antioxidants oxidative stress gut fermentation short chain fatty acids mucosal morphology broiler chickens perutnina pitovni piščanci prehrana živali oksidativni stres vročinski stres antioksidanti prebavila morfologija fermentacija true false true Angleški jezik Slovenski jezik Članek v reviji 2024-11-14 13:56:08 2024-11-14 13:56:10 2024-11-22 14:56:29 0000-00-00 00:00:00 2024 0 0 21 str. iss. 1, art. 64 Vol. 14 2024 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 636.5.084/.087 2077-0472 10.3390/agriculture14010064 179316995 agriculture-14-00064-v3.pdf agriculture-14-00064-v3.pdf 1 781E2336707D9A6EE0A6EB933FAD0AF9 e1d9cfabaef72d96e12ba546dca218eaaa490a9d3cb45fb9cc0bc0306752dd1d aa6e545e-a287-11ef-b232-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=195684 https://www.mdpi.com/2077-0472/14/1/64 1 75760ca6-a287-11ef-b232-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=195683 Biotehniška fakulteta Veterinarska fakulteta 0 0 0