20.500.12556/RUL-164866 Cysteine cathepsins from diagnosis to targeted therapy of cancer Cysteine cathepsins are a fascinating group of proteolytic enzymes that play diverse and crucial roles in numerous biological processes, both in health and disease. Understanding these proteases is essential for uncovering novel insights into the underlying mechanisms of a wide range of disorders, such as cancer. Cysteine cathepsins influence cancer biology by participating in processes such as extracellular matrix degradation, angiogenesis, immune evasion, and apoptosis. In this comprehensive review, we explore foundational research that illuminates the diverse and intricate roles of cysteine cathepsins as diagnostic markers and therapeutic targets for cancer. This review aims to provide valuable insights into the clinical relevance of cysteine cathepsins and explore their capacity to advance personalised and targeted medical interventions in oncology. anticancer therapy protease cystein cathepsin targeted drug delivery cancer diagnostic imaging onkološka terapija protirakavo zdravljenje proteaze cisteinski katepsin usmerjena dostava zdravil katepsini rak onkologija terapija z zdravili diagnostično slikanje true false true Angleški jezik Slovenski jezik Članek v reviji 2024-11-14 10:21:48 2024-11-14 10:21:53 2024-11-22 14:56:27 0000-00-00 00:00:00 2024 0 0 Str. 10-28 Vol. 226 Nov. 2024 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 577 1638-6183 10.1016/j.biochi.2024.09.001 214804227 1-s2.0-S0300908424002013-main.pdf 1-s2.0-S0300908424002013-main.pdf 1 D391C5DD1E131621FA13B32FB9259AC4 697b91b5c39c1ff7afe4b5a075b3d72a20177544637f8130bdb03e2204377acd 4f9e7e05-a26a-11ef-b232-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=195660 https://www.sciencedirect.com/science/article/pii/S0300908424002013 0 85268f44-a269-11ef-b232-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=195659 Fakulteta za kemijo in kemijsko tehnologijo 0 0 0