20.500.12556/RUL-163783 Review of history and mechanisms of action of lactulose (4-O-β-D-Galactopyranosyl-β-D-fructofuranose) present and future applications in food Lactulose is a synthetic disaccharide composed of galactose and fructose. Literature review of history, legal status and possible food applications of lactulose in functional foods, such as confectionery and beverages. In the colon, lactulose is fermented by the microbiota and acts as a selective modulator of bacterial growth, promoting the growth of Lactobacilli and Bifdobacteria. It generates organic acids, such as short-chain fatty acids and lactic acid, which lower the pH of the colon and act as an osmotic laxative. Lactulose was frst used in 1957 as an ingredient in an infant formula. Later it was registered as a prescription drug and banned for food use in many countries. In 2012, lactulose received an EU (European Union) health claim “contributes to acceleration of intestinal transit”. It can be used in food and food supplements across all age groups, from infants to the elderly. Lactulose has favourable technological properties, such as sweetness of 48–62% sucrose without an aftertaste, high solubility, low cariogenic potential and stability. Lactulose gummy candy, without added sweeteners, has an overall likability comparable to classic sucrose/glucose-based candy. With more than 60 years of safe use in infant, child, adult and elderly population, lactulose is an ideal ingredient for prebiotic functional food. Its technological properties allow for development of functional candy and beverages almost indistinguishable from those made from sucrose. lactulose functional food prebiotic gummy candy microbiota modulator hard candy funkcionalna živila prebiotiki laktuloza črevesna mikrobiota true false true Angleški jezik Slovenski jezik Članek v reviji 2024-10-10 15:29:30 2024-10-10 15:29:39 2024-10-12 03:56:09 0000-00-00 00:00:00 2024 0 0 Str. 2036–2045 iss. 11 Vol. 61 2024 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 613.292 0022-1155 10.1007/s13197-024-05997-z 194895107 s13197-024-05997-z.pdf s13197-024-05997-z.pdf 1 64E996CD7C1D27830DE6BB48AB5B0BAA 50aa38007e30fa365c6def2ec5164c19f326627df275a52b3558ccfecf6f4b9b e11e7c3d-870b-11ef-b232-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=193708 https://link.springer.com/article/10.1007/s13197-024-05997-z 0 c29b0e10-870b-11ef-b232-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=193707 Zdravstvena fakulteta Biotehniška fakulteta 0 0 0