20.500.12556/RUL-163378 Assessment of extracellular particles directly in plasma Extracellular nanoparticles (EPs) in blood have been amply studied since their biological role was indicated more than 50 years ago. Among the various types of nano-sized blood constituents, the studies outlined lipoproteins, immune complexes and extracellular particles. Efforts have been invested to separate or separately assess different types of particles. Recently, much attention has been devoted to extracellular vesicles (EVs), however, experimental evidence indicates that the methods used for their harvesting and assessment importantly influence the content of the samples whereas the information on characteristics of the samples that could reflect the clinical status of the sample donor may be altered. Recent developments of the characterization methods point to the possibility of assessing nano-sized EPs directly in plasma and blood, thereby avoiding artefacts caused by processing. In this contribution, we consider the assessment of nano-sized EPs from blood and provide evidence supporting the direct assessment of EPs in plasma. extracellular particles from blood extracellular particles from plasma interferometric light microscopy dynamic light scattering true false true Angleški jezik Ni določen Drugo 2024-10-04 14:17:33 2024-10-04 14:17:33 2024-10-09 03:48:14 0000-00-00 00:00:00 2024 0 0 Str. 71-77 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 577 10.55295/PSL.11.2024.8 210329603 205044227 RAZ_Korenjak_Bostjan_2024.pdf RAZ_Korenjak_Bostjan_2024.pdf 1 D16096E7712BD35A969FB798F62007E0 246bad35779d615a9305b2df23bba24dea2cc724b7dfa91f22c2358568ee4ae3 7916b637-824a-11ef-b232-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=192979 https://www.zf.uni-lj.si/images/zalozba/Sokratska_11/8_Korenjak_Bo%C5%A1tjan.pdf 0 abe95194-824a-11ef-b232-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=192980 Zdravstvena fakulteta Veterinarska fakulteta 0 0 0