20.500.12556/RUL-163032 Ugotavljanje nitrozaminov v izbranih kozmetičnih izdelkih Determination of nitrosamines in selected cosmetic products Z namenom ugotavljanja vsebnosti nitrozaminov v kozmetičnih izdelkih na slovenskem trgu smo le-te pregledali in primerjali njihovo formulacijo iz vidika potencialnega nastanka nitrozaminov. Sledil je razvoj postopka priprave vzorcev, primernih za analizo s predhodno razvito instrumentalno metodo na osnovi tekočinske kromatografije, sklopljene z masno spektrometrijo visoke ločljivosti. Metodo smo nato validirali in jo uporabili pri analizi realnih vzorcev poltrdnih kozmetičnih izdelkov. In order to determine the content of nitrosamines in cosmetic products on the Slovenian market, we examined them and compared their formulation from the point of view of the potential formation of nitrosamines. This was followed by the development of a procedure for preparing samples that are suitable for analysis using a previously developed instrumental method based on liquid chromatography coupled with high-resolution mass spectrometry. The method was then validated and used in the analysis of real samples of semi-solid cosmetic products. nitrozamini kozmetične sestavine vsebnost izkoristek ekstrakcije LC-HRMS nitrosamines cosmetic ingredients content extraction recovery LC-HRMS true false false Slovenski jezik Angleški jezik Magistrsko delo/naloga 2024-10-01 08:46:05 2024-10-01 08:46:07 2024-10-06 03:29:15 0000-00-00 00:00:00 2024 0 0 0000-00-00 NiDoloceno NiDoloceno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 1970-01-01 111165 25046.pdf 25046.pdf 1 51925AFE72F4A438F4E1FE9173E103E9 00df722bb8dc7e1d5be4702e29f0f022c9bad7931c4e628f0ddbd69258c8e437 af5b1155-7fc0-11ef-b232-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=192485 Fakulteta za farmacijo 0 0 0