20.500.12556/RUL-162455 Unveiling genetic potential for equine meat production a bioinformatics approach In view of the predicted significant increase in global meat production, alternative sources such as horsemeat are becoming increasingly important due to their lower environmental impact and high nutritional value. This study aimed to identify SNP markers on the GeneSeek® Genomic Profiler™ Equine (Neogen, Lansing, MI, USA) that are important for horsemeat production traits. First, orthologous genes related to meat yield in cattle and common genes between horses and cattle within QTLs for body size and weight were identified. Markers for these genes were then evaluated based on predicted variant consequences, GERP scores, and positions within constrained elements and orthologous regulatory regions in pigs. A total of 268 markers in 57 genes related to meat production were analyzed. This resulted in 27 prioritized SNP markers in 22 genes, including notable markers in LCORL, LASP1, IGF1R, and MSTN. These results will benefit smallholder farmers by providing genetic insights for selective breeding that could improve meat yield. This study also supports future large-scale genetic analyses such as GWAS and Genomic Best Linear Unbiased Prediction (GBLUP). The results of this study may be helpful in improving the accuracy of genomic breeding values. However, limitations include reliance on bioinformatics without experimental validation. Future research can validate these markers and consider a wider range of traits to ensure accuracy in equine breeding. bioinformatics equine genomics horsemeat production selective breeding SNP markers konji meso prireja genetika bioinformatika true false true Angleški jezik Slovenski jezik Članek v reviji 2024-09-24 04:16:01 2024-10-02 10:18:37 2025-01-17 13:15:17 0000-00-00 00:00:00 2024 0 0 22 str. iss. 16, art. 2441 Vol. 14 2024 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 636.1:637.5 2076-2615 10.3390/ani14162441 205403651 animals-14-02441-v2.pdf animals-14-02441-v2.pdf 1 7230093E59A03FD4E5B775F1694B3D06 9aa72b94c51292a2cd52d5afe58ff72e3fdff0eec079aff5916704c0d4af8918 4a07a7d7-8097-11ef-b232-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=192611 https://www.mdpi.com/2076-2615/14/16/2441 1 d3f96eb9-7a1a-11ef-b232-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=191785 Biotehniška fakulteta 0 0 0