20.500.12556/RUL-162300 Pregled načinov gojenja in aktivnih učinkovin glive Inonotus obliquus Cultivation and bioactive compounds of Inonotus obliquus fungi Inonotus obliquus, znan tudi kot chaga ali brezin luknjač, je cenjena zdravilna goba tako v tradicionalni kot v sodobni medicini. Kot je prikazano v tem diplomskem delu, gliva izkazuje širok spekter terapevtskih lastnosti. Uporablja se v terapevtske namene že od 12. stoletja, zlasti v ljudskem zdravilstvu, kjer so jo uporabljali za zdravljenje bolezni, kot so rak prebavil, sladkorna bolezen, bakterijske okužbe in bolezni jeter. Sodobne raziskave potrjujejo terapevtske učinke izvlečkov glive Inonotus obliquus, ki vključujejo protivnetne, antioksidativne, protirakave, antidiabetične, proti debelosti usmerjene, hepatoprotektivne, renoprotektivne, protibakterijske, protivirusne in proti utrujenosti delujoče lastnosti. Ugotovljeno je bilo, da so za te učinke odgovorne bioaktivne spojine, kot so polisaharidi, triterpenoidi, polifenoli in ligninski metaboliti. Pomembno je tudi preučiti morebitne antagonistične ali sinergistične interakcije med Inonotus obliquus in drugimi spojinami ali zdravili, če jih uporabljamo sočasno. Zato je nujno uporabiti najsodobnejše tehnologije in eksperimentalne metode za izvedbo obsežnih študij, ki bodo še dodatno osvetlile potencial te glive kot terapevtskega sredstva. Inonotus obliquus, also known as chaga, is a valued medicinal mushroom in both traditional and modern medicine. As shown in this thesis, the mushroom has a wide range of therapeutic properties. It has been used for therapeutic purposes since the 12th century, especially in folk medicine, where it was used to treat diseases such as gastrointestinal cancer, diabetes, bacterial infections and liver diseases. Modern research confirms the therapeutic effects of Inonotus obliquus extracts, which include anti-inflammatory, antioxidant, anti-cancer, anti-diabetic, anti-obesity, liver-protective, kidney-protective, antibacterial, antiviral and anti-fatigue properties. Bioactive compounds such as polysaccharides, triterpenoids, polyphenols and lignin metabolites have been identified as responsible for these effects. It is also important to consider possible antagonistic or synergistic interactions between Inonotus obliquus and other compounds or drugs when used simultaneously. It is therefore essential to utilise state-of-the-art technologies and experimental methods to conduct large-scale studies that will further elucidate the potential of this mushroom as a therapeutic agent. Inonotus obliquus chaga brezin luknjač bioaktivne spojine Inonotus obliquus chaga bioactive compounds true false false Slovenski jezik Angleški jezik Diplomsko delo/naloga 2024-09-21 07:16:15 2024-09-21 07:16:23 2024-09-24 03:32:21 0000-00-00 00:00:00 2024 0 0 0000-00-00 NiDoloceno NiDoloceno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 246053 208460035 44031.pdf 44031.pdf 1 762228EE332BC2FD74561D6B7C29A73A d1a91e1931dac21dc2bb7581a805a845277004be41a6f8d435e1bf5ab2b6686c 882288da-77d8-11ef-b232-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=191506 Biotehniška fakulteta 0 0 0