20.500.12556/RUL-160092 Inhalacijska biodostopnost kemijskih zvrsti svinca Inhalation bioaccessibility of lead chemical species V zadnjih desetletjih je onesnaženost s potencialno strupenimi elementi (PSE) postala resen problem. Izpust prašnih delcev, ki vsebujejo PSE, v ozračje in tla ogroža zdravje ljudi in svinec je med bolj nevarnimi elementi. V diplomskem delu sem določila inhalacijsko biodostopnost svinca v nekaterih okoljsko relevantnih kemijskih zvrsteh svinca in v izbranih realnih okoljskih vzorcih, ki vsebujejo povišane koncentracije svinca. Kot ekstrakcijsko sredstvo sem uporabila umetno lizosomalno raztopino (ALF). Proučevala sem tudi vpliv izpostavljenosti izbranih kemijskih zvrsti svinca okolju s povišano vsebnostjo vlage na kemijske spremembe vzorcev in posledično tudi na njihovo biodostopnost. Biodostopnost svinca v proučevanih kemijskih zvrsteh svinca ni visoka, a se je pri vzorcih, predhodno staranih v komori s stalno vlago, povišala. Tudi inhalacijske biodostopnosti svinca v izbranih okoljskih vzorcih so visoke. Z XRD analizo sem na difraktogramih kemijskih zvrsti svinca po staranju v komori s stalno vlago zaznala pojav novih kristaliničnih zvrsti le pri vzorcu PbO. Na slikah SEM opazimo spremembo pri vseh vzorcih, medtem ko je EDS analiza pokazala spremembo elementne sestave pri vzorcih PbO in PbS. Pollution with potentially toxic elements (PTE) has become a serious problem in recent decades. The release of PTE dust particles into the atmosphere and soil threatens human health and lead is one of the more dangerous elements. In my bachelor's thesis, I determined the inhalation bioaccessibility of lead in some environmentally relevant chemical lead species and in selected real environmental samples with elevated lead concentrations. An artificial lysosomal solution (ALF) was used as an extraction agent. The impact of exposure of selected chemical lead species to an environment with increased moisture content on the chemical changes of the samples and consequently on their bioaccessibility was also studied. The bioaccessibility of lead in the investigated chemical species is not high, but it was increased in samples previously aged in a chamber with a constant humidity. The inhalation bioaccessibility of lead in selected environmental samples is also high. By XRD analysis, the appearance of new crystalline species was detected on the diffractograms of the chemical lead species after ageing in a chamber with constant humidity only in the case of PbO sample. In the SEM images, a change in morphology can be observed in all samples, while the EDS analysis revealed a change in the elemental composition in the PbO and PbS samples. biodostopnost cestni prah inhalacija jalovina svinec tla bioaccessibility inhalation lead road dust soil tailings true false false Slovenski jezik Angleški jezik Diplomsko delo/naloga 2024-08-19 14:50:01 2024-08-19 14:50:05 2024-08-29 10:50:44 0000-00-00 00:00:00 2024 0 0 0000-00-00 NiDoloceno NiDoloceno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 22716 205722371 Zidaric_Nina_-_Inhalacijska_biodostopnost_kemijskih_zvrsti_svinca.pdf Zidaric_Nina_-_Inhalacijska_biodostopnost_kemijskih_zvrsti_svinca.pdf 1 DAD1B8669AC24A1922EF97079F6C5BA5 d12ac863840263e6859990a4a88d93198fad06f2ce6bf34d4ab48af4db6e1266 5ebc4782-5e29-11ef-8f74-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=188551 Fakulteta za kemijo in kemijsko tehnologijo 0 0 0