20.500.12556/RUL-158986 The versatile and strategic O-carbamate directed metalation group in the synthesis of aromatic molecules an update The aryl O-carbamate (ArOAm) group is among the strongest of the directed metalation groups (DMGs) in directed ortho metalation (DoM) chemistry, especially in the form Ar-OCONEt$_2$. Since the last comprehensive review of metalation chemistry involving ArOAms (published more than 30 years ago), the field has expanded significantly. For example, it now encompasses new substrates, solvent systems, and metalating agents, while conditions have been developed enabling metalation of ArOAm to be conducted in a green and sustainable manner. The ArOAm group has also proven to be effective in the anionic ortho-Fries (AoF) rearrangement, Directed remote metalation (DreM), iterative DoM sequences, and DoM-halogen dance (HalD) synthetic strategies and has been transformed into a diverse range of functionalities and coupled with various groups through a range of cross-coupling (CC) strategies. Of ultimate value, the ArOAm group has demonstrated utility in the synthesis of a diverse range of bioactive and polycyclic aromatic compounds for various applications. aryl O-carbamate metalation rearrangement cross coupling regioselective directing group aromatic compounds hydrocarbons organic compounds aril O-karbamat metalizacija preureditev navzkrižna sklopitev regioselektivnost usmerjevalna skupina true false true Angleški jezik Slovenski jezik Članek v reviji 2024-06-26 12:57:09 2024-06-26 12:57:10 2024-07-07 03:28:43 0000-00-00 00:00:00 2024 0 0 Str. 7731–7828 iss. 12 Vol. 124 2024 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 547.52.057 0009-2665 10.1021/acs.chemrev.3c00923 198743811 jansen-van-vuuren-et-al-2024-the-versatile-and-strategic-o-carbamate-directed-metalation-group-in-the-synthesis-of.pdf jansen-van-vuuren-et-al-2024-the-versatile-and-strategic-o-carbamate-directed-metalation-group-in-the-synthesis-of.pdf 1 9BC4AC4BEFF358768AE8AEE3FD0F2CD3 16708a14347db6640426b78cf9fd5f206a9cacccc50970e8501e8b897c9e5033 09bf3164-33ae-11ef-8fa5-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=186732 https://pubs.acs.org/doi/10.1021/acs.chemrev.3c00923 1 d6f9f09e-33aa-11ef-8fa5-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=186730 Fakulteta za kemijo in kemijsko tehnologijo 0 0 0