20.500.12556/RUL-155013 Omics mass spectrometry analysis of canine plasma Blood derived products, such as autologous plasma, have high clinical importance and are applied in numerous therapeutic fields. The preparation of autologous plasma from the patient's own blood is easy to perform by centrifugation, however, the preparation procedure can significantly affect the blood cells, platelets and vesicles in the sample. Therefore, it is of utmost importance to understand the impact of sample processing on the chemical composition of plasma preparations as well as on their biological activity. Here, we present a mass spectrometry-based plasma profiling method in which three compound groups: lipids, proteins and glycoproteins are analysed in a single workflow. Analysis of the chemical composition of plasma samples prepared by different centrifugation protocols revealed differences in the lipid and glycoprotein profiles, demonstrating the importance of standardized protocols for the preparation of plasma products. plasma lipids proteins glycoproteins mass spectrometry ion mobility true false true Angleški jezik Ni določen Neznano 2024-03-14 07:32:58 2024-03-14 07:32:58 2024-09-11 04:23:00 0000-00-00 00:00:00 2024 0 0 Str. 67-72 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 577 10.55295/PSL.2024.I11 188787459 186758147 11_Schlosser_Gitta.pdf 11_Schlosser_Gitta.pdf 1 74777E4E25DF1278633797845D79EC2F d62ccbf3775fc5474b0449e84ed0df4cbab168475d43a7a381f0a4a0e55a7ffd 71f8aadb-6f4b-11ef-b232-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=190275 https://www.zf.uni-lj.si/si/predstavitev/zalozba/socratic-lectures-10-part-i 0 6c33c6f8-6f4b-11ef-b232-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=190274 Zdravstvena fakulteta Fakulteta za elektrotehniko Veterinarska fakulteta 0 0 0