20.500.12556/RUL-154948 Monitoring of caffeine consumption effect on skin blood properties by diffuse reflectance spectroscopy Caffeine is the most widely consumed psychoactive substance worldwide, affecting numerous tissues and organs, with notable impacts on the central nervous system, heart, and blood vessels. The effect of caffeine on vascular smooth muscle cells is an initial transient contraction followed by significant vasodilatation. In this study we investigate the use of diffuse reflectance spectroscopy (DRS) for monitoring of vascular changes in human skin induced by caffeine consumption. DRS spectra were recorded on volar sides of the forearms of eight healthy volunteers at time intervals of 0, 30, 60, 120, and 180 min after consumption of caffeine, while one subject served as a negative control. Analytical diffusion approximation solutions for diffuse reflectance from three-layer structures were used to assess skin composition (e.g. dermal blood volume fraction and oxygen saturation) by fitting these solutions to experimental data. The results demonstrate that cutaneous vasodynamics induced by caffeine consumption can be monitored by DRS, while changes in the control subject not consuming caffeine were insignificant. medical physics diffuse reflectance spectroscopy caffeine human skin caffeine consumption diffuse reflectance spectra inverse diffusion approximation medicinska fizika difuzna refleksijska spektroskopija kofein človeška koža true false true Angleški jezik Slovenski jezik Članek v reviji 2024-03-11 13:08:03 2024-03-11 13:08:04 2024-09-12 13:27:50 0000-00-00 00:00:00 2024 0 0 Str. 47-56 iss. 1 Vol. 73 2024 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 543.424.4:616-073 1802-9973 10.33549/physiolres.935138 188395267 73_47.pdf 73_47.pdf 1 BC46DE4BD6703B461BB968281450EF54 89343563fd6f47dc2870778054e9e204a66c999811830fdda26208563c08f9ab 658718d7-dfa0-11ee-a66a-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=181616 https://www.biomed.cas.cz/physiolres/2024/1_24.htm 0 e89729e8-70f6-11ef-b232-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=190551 Fakulteta za matematiko in fiziko 0 0 0