20.500.12556/RUL-154836 Catalytic performance of Noyori–Ikariya-type ruthenium complex with tethered syn-ULTAM ligand for the asymmetric transfer hydrogenation of ketones The ruthenium complex of the tethered syn-ULTAM ligand, i.e. syn-3-(α-aminobenzyl)-benzo-γ-sultam, has been evaluated for the asymmetric transfer hydrogenation (ATH) of a variety of ketones in formic acid/triethylamine mixture. Its performance was similar to the established Noyori–Ikariya-type catalysts for the reduction of benzo-fused cyclic ketones, but the enantioselectivity for the reduction of acetophenone was only moderate. The syn-ULTAM-based catalyst was particularly efficient and enantioselective for ATH of the sterically demanding α,α-disubstituted ketones. Moreover, we report a divergent ATH of 2-phenyl-1,3-indandione to either cis-2-phenyl-1-indanol, or cis,trans-2-phenyl-1,3-indandiol. asymmetric synthesis ruthenium hydrogenation alcohol asimetrična sinteza rutenij hidrogenacija hidrogeniranje alkohol true false true Angleški jezik Slovenski jezik Članek v reviji 2024-03-05 12:45:17 2024-03-05 12:45:21 2024-05-21 14:32:33 0000-00-00 00:00:00 2024 0 0 4 str. Vol. 138, art. 154984 2024 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 66.094.1 0040-4039 10.1016/j.tetlet.2024.154984 187162371 1-s2.0-S0040403924000789-main.pdf 1-s2.0-S0040403924000789-main.pdf 1 5637C1E7E929E74C4C5B5D518B7D65FF c53acb0b13605f7e3e6a870d5a5e9043f4165944c818103d3fb712c03f5e9ed8 3865449b-dae6-11ee-a8be-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=181450 https://www.sciencedirect.com/science/article/pii/S0040403924000789 1 d82765f0-dae5-11ee-a8be-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=181449 Fakulteta za farmacijo 0 0 0