20.500.12556/RUL-154050 Cardio-respiratory and muscle oxygenation responses to submaximal and maximal exercise in normobaric hypoxia comparison between children and adults As differential physiological responses to hypoxic exercise between adults and children remain poorly understood, we aimed to comprehensively characterise cardiorespiratory and muscle oxygenation responses to submaximal and maximal exercise in normobaric hypoxia between the two groups. Following familiarisation, fifteen children (Age = 9 ± 1 years) and fifteen adults (Age = 22 ± 2 years) completed two graded cycling exercise sessions to exhaustion in a randomized and single-blind manner in normoxia (NOR; F$_i$O$_2$ = 20.9) and normobaric hypoxia (HYP; F$_i$O$_2$ = 13.0) exercises conditions. Age-specific workload increments were 25 W·3 min$^{−1}$ for children and 40 W·3 min$^{−1}$ for adults. Gas exchange and vastus lateralis oxygenation parameters were measured continuously via metabolic cart and near-infrared spectroscopy, respectively. Hypoxia provoked significant decreases in maximal power output P$_{MAX}$ (children = 29%; adults 16% (F = 39.3; p < 0.01)) and power output at the gas exchange threshold (children = 10%; adults:18% (F = 8.08; p = 0.01)) in both groups. Comparable changes were noted in most respiratory and gas exchange parameters at similar power outputs between groups. Children, however, demonstrated, lower P$_{ET}$CO$_2$ throughout the test at similar power outputs and during the maintenance of $\dot{V}$CO$_2$ at the maximal power output. These data indicate that, while most cardiorespiratory responses to acute hypoxic exercise are comparable between children and adults, there exist age-related differential responses in select respiratory and muscle oxygenation parameters. sport hypoxemia exercise ventilation muscle oxygenation age adults children maturation šport hipoksemija telovadba vadba prezračevanje oksigenacija mišic starost odrasli otroci staranje true false true Angleški jezik Slovenski jezik Članek v reviji 2024-01-22 12:23:23 2024-01-22 12:23:24 2024-01-23 03:38:31 0000-00-00 00:00:00 2023 0 0 14 str. iss. 3, art. 457 Vol. 12 2023 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 796.01 2079-7737 10.3390/biology12030457 145498627 biology-12-00457.pdf biology-12-00457.pdf 1 C834CEED017508D6804201E787EA0AC0 c8e74db5448ef49511c97d93c5a400f2e57957b1188a2904eb38f4e21e005f80 57639668-b919-11ee-88cd-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=180197 https://www.mdpi.com/2079-7737/12/3/457 1 a9ab02c9-b918-11ee-88cd-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=180196 Fakulteta za šport 0 0 0