20.500.12556/RUL-152847 Histologic changes of porcine portal vein anastomosis after electrochemotherapy with bleomycin Electrochemotherapy (ECT) is used for treatment of unresectable abdominal malignancies. This study aims to show that ECT of porcine portal vein anastomosis is safe and feasible in order to extend the indications for margin attenuation after resection of locally advanced pancreatic carcinoma. No marked differences were found between the control group and ECT treated groups. Electroporation thus caused irreversible damage to the vascular smooth muscle cells in tunica media that could be due to the narrow irreversible electroporation zone that may occur near the electrodes, or due to vasa vasorum thrombosis in the tunica externa. Based on the absence of vascular complications, and similar histological changes in lienal vein anastomosis, we can conclude that ECT of portal vein anastomosis is safe and feasible. electrochemotherapy portal vein anastomosis pancreatic cancer elektrokemoterapija anastomoza portalne vene rak trebušne slinavke true false true Angleški jezik Slovenski jezik Članek v reviji 2023-12-08 16:27:23 2023-12-08 16:27:26 2023-12-09 03:49:42 0000-00-00 00:00:00 2023 0 0 10 str. Vol. 154, art. 108509 Dec. 2023 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 616.3 1878-562X 10.1016/j.bioelechem.2023.108509 159036675 1-s2.0-S1567539423001469-main.pdf 1-s2.0-S1567539423001469-main.pdf 1 FF9187AE85E8C61E929A2166F8A6E69F 38e062986fa939a9757c8a372e818bd72c414113106ac9318b34b51198f7b20b af8af186-95de-11ee-9c20-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=178544 https://www.sciencedirect.com/science/article/pii/S1567539423001469 0 a67d0b19-95de-11ee-9c20-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=178543 Medicinska fakulteta Veterinarska fakulteta Zdravstvena fakulteta 0 0 0