20.500.12556/RUL-152752 Antifungal effect of polymethyl methacrylate resin base with embedded Au nanoparticles Full and partial restorations in dentistry must replicate the characteristics of the patient’s natural teeth. Materials must have good mechanical properties and be non-toxic and biocompatible. Microbes, which can form biofilms, are constantly in contact with restorations. In this study, we investigate how well Candida albicans adheres to a polymethyl methacrylate (PMMA) resin base with gold (Au) nanoparticles. We synthesized Au nanoparticles and characterized them. The average size of Au nanoparticles embedded in PMMA was 11 nm. The color difference ∆E between PMMA and PMMA/Au composites was 2.7 and was still esthetically acceptable to patients. PMMA/Au surfaces are rougher and more hydrophilic than pure PMMA surfaces, and the isoelectric point of both types of surfaces was 4.3. Above the isoelectric point, PMMA/Au surfaces are more negatively charged than PMMA surfaces. The added Au nanoparticles decreased the tensile strength, while the hardness did not change significantly. Adhesion measurements showed that PMMA surfaces modified with Au nanoparticles reduced the extent of microbial adhesion of Candida albicans. fungal adhesión C. albicans polymethyl methacrylate resin Au surface properties composites adhezija gliv C. albicans polimetilmetakrilat Au lastnosti površine kompoziti true false true Angleški jezik Slovenski jezik Članek v reviji 2023-12-06 09:23:30 2023-12-06 09:23:35 2023-12-07 03:45:48 0000-00-00 00:00:00 2023 0 0 15 str. iss. 14, art. 2128 Vol. 13 2023 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 2023-01-01 66 2079-4991 10.3390/nano13142128 159528707 nanomaterials-13-02128-v3.pdf nanomaterials-13-02128-v3.pdf 1 A930E61F567E930800587EF88CE3E048 f7175beebc91339fd27875baf79e4729534b80e2e9e5be4ceebb6034c0079d99 e636c15f-9410-11ee-ac6f-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=178386 https://www.mdpi.com/2079-4991/13/14/2128 1 c11e58ec-9410-11ee-ac6f-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=178385 Zdravstvena fakulteta Biotehniška fakulteta 0 0 0