20.500.12556/RUL-152427 Analiza nestacionarnega prenosa toplote v bioreaktorju Analysis of transient heat transfer in a bioreactor V magistrskem delu je prikazana analiza nestacionarnega prenosa toplote v 50-litrskem bioreaktorju, ki je namenjen gojenju bakterijske kulture v farmacevtskem laboratoriju. Predvideli smo segrevanje in hlajenje z dvojnim plaščem, po potrebi pa še z dodatnimi cevnimi zankami. Najprej smo komponentam na osnovi priporočil določili dimenzije. Nato smo izvedli preračun za proces segrevanja na sterilizacijsko temperaturo in ohlajanja na delovno temperaturo. Sledila je obravnava vplivnih parametrov, pri čemer smo se osredotočili predvsem na variacije pretokov in vstopnih temperatur v procesni sistem. V programu SIMIT smo zasnovali digitalni dvojček sistema in naposled izvedli primerjavo rezultatov analitičnega in simulacijskega preračuna. In Master thesis, we analysed transient heat transfer in bioreactor with capacity of 50 liters, which is used in farmaceutical laboratory for bacterial culture cultivation. Heating and cooling are achieved with double jacket, and when needed, with additional tube baffles also. First, we defined the dimensions of the components according to recommendations. Then, we performed calculation for the process of heating to sterilization temperature followed by cooling to working temperature. We then analyzed critical parameters, where we focused on current variations and input temperatures into the process system. We designed system’s digital twin in program SIMIT, and finally, compared results of analytical and simulative calculation. nestacionarni prenos toplote bioreaktor dvojni plašč cevne zanke digitalni dvojček transient heat transfer bioreactor double jacket tube baffles digital twin true false false [M. Levak] Slovenski jezik Angleški jezik Magistrsko delo/naloga 2023-11-24 09:51:59 2023-11-24 09:52:02 2024-01-31 12:34:38 0000-00-00 00:00:00 2023 0 Ljubljana 0 XX, 74 str. 0000-00-00 NiDoloceno NiDoloceno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 536.2:602.42-7:577.152.3(043.2) 259627 183199747 32556.pdf 32556.pdf 1 7EC9DA09020EBAF96736FCEBCB27A4FE 797ccc0d6a74bc75e8ad1a39d6836d113bf2e12291e9e7837e84999e3a82b579 bef495cd-8aa6-11ee-8840-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=177944 Fakulteta za strojništvo 0 0 0