20.500.12556/RUL-152151 Mehanizem delovanja diete z nizko vsebnostjo FODMAP pri bolnikih s sindromom razdražljivega črevesja Mechanism of action of a low FODMAP diet on patients with irritable bowel syndrome Namen diplomske naloge je bil pregled literature na temo sindroma razdražljivega črevesja (SRČ) in njegovo trenutno zdravljenje. SRČ je ena izmed najpogostejših gastrointestinalnih motenj, ki prizadene milijone ljudi po celem svetu. Glede na trenutno diagnostiko z Rimskimi IV kriteriji, je za SRČ značilna bolečina v trebuhu, povezana z nerednim/prepogostim odvajanjem blata, brez organskih vzrokov. Znano je da večina bolnikov s SRČ povezuje svoje gastrointestinalne simptome z uživanjem hrane, zaradi česar so bile za lajšanje simpotomov razvite različne prehranske manipulacije. Dieta z nizko vsebnostjo fermentabilnih oligosaharidov, disaharidov, monosaharidov in poliolov (FODMAP) je sprožila največje znanstveno in klinično zanimanje, in je še vedno predmet raziskav. Zelo pomembno vlogo pri lajšanju težav SRČ imajo tudi različni probiotiki ter številne druge bioaktivne snovi iz hrane. Ker je SRČ dokaj na novo oprodeljena funkcionalna bolezen, je razumevanje in zdravljenje le te še dokaj neraziskano in pomanjkljivo. Večina raziskav, ki so opravljene z različnimi dietami, tudi FODMAP dieto so še vedno predmet številnih kliničnih raziskav. Za boljše razumevanje so potrebne dodatne raziskave, ki bodo temeljile in se osredotočale na različne skupine posameznikov. The aim of this thesis is to review the current literature on irritable bowel syndrome (IBS) and its current treatment. IBS is one of the most common gastrointestinal disorders affecting millions of people worldwide. According to the current diagnosis with the Rome IV criteria, IBS is characterised by abdominal pain associated with defecation and/or a change in bowel habits, with no detectable organic cause. It is well known that most patients with IBS associate their gastrointestinal symptoms with food intake, and therefore treatment with specific dietary manipulation has become a very attractive strategy. Diets low in fermented oligosaccharides, disaccharides, monosaccharides and polyols (FODMAPs) have generated the greatest scientific and clinical interest and are still under continuous investigation. The probiotics and many other bioactive compounds in food also play a very important role in the process of treating the disease. As IBS is one of the newer disorders there is a lack of knowledge in this area. Most of the research that has been done on different diets and low FODMAP diet is still being researched. Further research, which are based and focusing on different groups of individuals, are needed to better understand. sindrom razdražljivega črevesja mikrobiota dietna prehrana dieta z nizko vsebnostjo FODMAP irritable bowel syndrome microbiota diet low FODMAP diet true false false [V. Pankov] Slovenski jezik Angleški jezik Diplomsko delo/naloga 2023-11-08 07:15:18 2023-11-08 07:15:30 2025-08-08 13:27:57 0000-00-00 00:00:00 2023 0 0 0000-00-00 NiDoloceno NiDoloceno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 613.2+612.3:616.34 235522 171269635 38147.pdf 38147.pdf 1 25632CF05F4C2B60882EA50C4F48F2C6 d065624467c93528e89a3ca6052fe51aadca4e2900805c6b4d9ac4637b271c08 3d2d62a5-7dfe-11ee-ae69-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=177450 Biotehniška fakulteta 0 0 0